235989

Brij^® L4

average M_n ~362

• Synonyme(s) : Polyethylene glycol dodecyl ether, Polyoxyethylene (4) lauryl ether
• Formule linéaire : (C₂₀H₄₂O₅)_n
• CAS Number: 9002-92-0
• Numéro MDL: MFCD00043063
• Code UNSPSC : 12161900
• ID de substance PubChem : 24854130
• Nomenclature NACRES : NA.21

Propriétés

• Description: non-ionic
• Niveau de qualité: 200
• Poids mol.: average M_n ~362
• Indice de réfraction: n20/D 1.451 (lit.)
• Densité: 0.95 g/mL at 25 °C (lit.)
• HLB: 9
• Chaîne SMILES: CCCCCCCCCCCCOCCOCCOCCOCCO
• InChI: 1S/C20H42O5/c1-2-3-4-5-6-7-8-9-10-11-13-22-15-17-24-19-20-25-18-16-23-14-12-21/h21H,2-20H2,1H3
• Clé InChI: WPMWEFXCIYCJSA-UHFFFAOYSA-N

Description

Description générale

Brij^® L4 is a non-ionic surfactant. It comprises an alkyl (C12) tail attached to an oxyethylene headgroup.

Application

Brij^® L4 has been used:

• as a surfactant for the synthesis of copper(I) oxide (Cu₂O) spherical nanoparticles using a microemulsion technique
• as a non-ionic surfactant for preparing reverse micelles to synthesize Pt₃Co alloy nanoparticles
• as a surfactant to enhance the efficiency of interfacial coupling of hydrophobic materials and to make hydrogel

Actions biochimiques/physiologiques

Brij^® L4 exhibits amphiphilic properties. Brij L4 contains hydrophobic and hydrophilic regions that can form micelles and disperse hydrophobic drugs into the core of micelles. This in turn enhances drug solubility. Brij L4 also elicits a strong inhibitory effect against breast cancer resistance protein (BCRP) mediated drug efflux. It inhibits Taq adsorption better when compared to other commonly used surfactants. Brij L4 supports droplet polymerase chain reaction (PCR) in picoliter reaction volumes at standard Taq concentrations.

Informations légales

Brij is a registered trademark of Croda International PLC

Informations sur la sécurité

• Pictogrammes: GHS07,GHS09
• Mention d'avertissement: Warning
• Mentions de danger: H302,H315,H319,H411
• Conseils de prudence: P264 - P273 - P280 - P301 + P312 - P302 + P352 - P305 + P351 + P338
• Classification des risques: Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Irrit. 2 - Skin Irrit. 2
• Code de la classe de stockage: 10 - Combustible liquids
• Classe de danger pour l'eau (WGK): WGK 2
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable
• Équipement de protection individuelle: dust mask type N95 (US), Eyeshields, Gloves