282820

Protoporphyrin IX zinc(II)

guanylate cyclase inhibitor

• Synonyme(s) : 3,7,12,17-Tetramethyl-8,13-divinyl-2,18-porphinedipropionic acid, 8,13-Divinyl-3,7,12,17-tetramethyl-21H,23H-porphine-2,18-dipropionic acid zinc derivative, Protoporphyrin IX zinc(II) complex
• Formule empirique (notation de Hill) : C₃₄H₃₂N₄O₄Zn
• CAS Number: 15442-64-5
• Poids moléculaire : 626.03
• Numéro CE : 239-455-7
• Numéro MDL: MFCD00011612
• Code UNSPSC : 12171500
• ID de substance PubChem : 24857074
• Nomenclature NACRES : NA.47

Propriétés

• Niveau de qualité: 100
• Essai: ≥92% (HPLC)
• Forme: powder
• Technique(s): titration: suitable
• Couleur: red to very dark red
• λmax: 426 nm
• ε (coefficient d'extinction): ≥10000 at 585-591 nm in pyridine; ≥12000 at 548-554 nm in pyridine; ≥135000 at 423-429 nm in pyridine
• Application(s): diagnostic assay manufacturing; hematology; histology
• Température de stockage: room temp
• Chaîne SMILES: Cc1c(CCC(O)=O)c2cc3c(CCC(O)=O)c(C)c4cc5nc(cc6c(C)c(C=C)c(cc1n2)n6[Zn]n34)c(C=C)c5C
• InChI: 1S/C34H34N4O4.Zn/c1-7-21-17(3)25-13-26-19(5)23(9-11-33(39)40)31(37-26)16-32-24(10-12-34(41)42)20(6)28(38-32)15-30-22(8-2)18(4)27(36-30)14-29(21)35-25;/h7-8,13-16H,1-2,9-12H2,3-6H3,(H4,35,36,37,38,39,40,41,42);/q;+2/p-2/b25-13-,26-13-,27-14-,28-15-,29-14-,30-15-,31-16-,32-16-;
• Clé InChI: FUTVBRXUIKZACV-RGGAHWMASA-L

Description

Description générale

Protoporphyrin IX zinc(II) (ZnPP) is an anti-oxidant enzyme heme oxygenase-1.

Application

Cellular melanin content in normal human melanocytes treated with ZnPP has been studied. 1 It was used as a standard in a study where the excess formation of ZnPP in iron deficient erythropoiesis was determined by haematofluorometer.

Inhibits soluble guanylate cyclase.

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable
• Équipement de protection individuelle: Eyeshields, Gloves, type N95 (US)