A1028

8-Anilino-1-naphthalenesulfonic acid

≥97% purity (HPLC), powder

• Synonyme(s) : N-Phenyl peri acid, ANS, ANSA
• Formule linéaire : C₆H₅NHC₁₀H₆SO₃H
• CAS Number: 82-76-8
• Poids moléculaire : 299.34
• Beilstein: 1843887
• Numéro MDL: MFCD00003998
• Code UNSPSC : 12171500
• ID de substance PubChem : 24890494
• Nomenclature NACRES : NA.47

Propriétés

• Product Name: 8-Anilino-1-naphthalenesulfonic acid,
• Essai: ≥97% (HPLC)
• Niveau de qualité: 200
• Forme: powder
• Composition: , <0.5% (solvent)
• Couleur: black; gray to dark green
• Pf: 215-217 °C (dec.) (lit.)
• Solubilité: DMF: 50 mg/mL
• Application(s): diagnostic assay manufacturing; hematology; histology
• Température de stockage: room temp
• Chaîne SMILES: OS(=O)(=O)c1cccc2cccc(Nc3ccccc3)c12
• InChI: 1S/C16H13NO3S/c18-21(19,20)15-11-5-7-12-6-4-10-14(16(12)15)17-13-8-2-1-3-9-13/h1-11,17H,(H,18,19,20)
• Clé InChI: FWEOQOXTVHGIFQ-UHFFFAOYSA-N

Description

Application

8-Anilino-1-naphthalenesulfonic acid (ANS) has been used to study the thermal aggregation of BSA (bovine serum albumin).

Actions biochimiques/physiologiques

8-Anilino-1-naphthalenesulfonic acid (ANS) is an important dye which is used to study the intermediate states in the folding/unfolding pathways of proteins. It is also useful to check the conformational changes involved with the aggregation of proteins. ANS is nonfluorescent in the aqueous solution, however, it fluoresces strongly upon binding to BSA (bovine serum albumin) and denatured proteins. It is used for the detection of albumin in the serum. ANS mainly interacts with the solvent exposed nonpolar (hydrophobic) sites.

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable