S3674

Acide succinique

BioXtra, BioRenewable, ≥99.0%

• Synonyme(s) : Acide butanedioïque
• Formule linéaire : HOOCCH₂CH₂COOH
• CAS Number: 110-15-6
• Poids moléculaire : 118.09
• Beilstein: 1754069
• Numéro CE : 203-740-4
• Numéro MDL: MFCD00002789
• Code UNSPSC : 12352106
• ID de substance PubChem : 24899568
• Nomenclature NACRES : NA.25

Propriétés

• Niveau de qualité: 200
• Gamme de produits: BioXtra
• Essai: ≥99.0%
• Caractéristiques du produit alternatif plus écologique: Use of Renewable Feedstocks; Learn more about the Principles of Green Chemistry.
• sustainability: Greener Alternative Product
• Impuretés: ≤0.01% Insoluble matter
• Résidus de calcination: ≤0.02%
• pb: 235 °C (lit.)
• Pf: 184-186 °C (lit.)
• Solubilité: H₂O: 0.5 M, clear, colorless
• Traces d'anions: chloride (Cl^-): ≤0.001%; sulfate (SO₄^2-): ≤0.003%
• Traces de cations: Al: ≤0.0005%; Ca: ≤0.001%; Cu: ≤0.0005%; Fe: ≤0.0005%; K: ≤0.005%; Mg: ≤0.0005%; NH₄⁺: ≤0.05%; Na: ≤0.005%; Pb: ≤0.001%; Zn: ≤0.0005%
• Autre catégorie plus écologique: , Aligned
• Chaîne SMILES: OC(=O)CCC(O)=O
• InChI: 1S/C4H6O4/c5-3(6)1-2-4(7)8/h1-2H2,(H,5,6)(H,7,8)
• Clé InChI: KDYFGRWQOYBRFD-UHFFFAOYSA-N

Description

Description générale

We are committed to bringing you Greener Alternative Products, which adhere to one or more of The 12 Principles of Greener Chemistry. This product is biobased and thus aligns with "Use of Renewable Feedstocks". Click here for more information.

Application

Succinic acid has been used:

• in succinate dehydrogenase mitochondrial assay.
• as an internal standard in mass spectroscopy.
• as succinate dehydrogenase substrate in oxygraph analysis to measure respiration rates.

Actions biochimiques/physiologiques

Succinic acid is a byproduct of anaerobic fermentation in microbes. It is a dicarboxylic acid and an intermediate in Kreb′s cycle. Polymorphism in succinate dehydrogenase leads to succinate accumulation. High levels of succinate impairs 2-oxoglutarate epigenetic signalling. Succinate levels may modulate tumor progression. Succinate inhibits histone demethylation and may contribute to epigenetic changes. Succinate is crucial for interleukin-1 β (IL-1β) synthesis during inflammation and immune signalling.

Autres remarques

Succinic Acid: A New Platform Chemical for Biobased Polymers from Renewable Resources

Informations sur la sécurité

• Pictogrammes: GHS05
• Mention d'avertissement: Danger
• Mentions de danger: H318
• Conseils de prudence: P280 - P305 + P351 + P338
• Classification des risques: Eye Dam. 1
• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 1
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable
• Équipement de protection individuelle: dust mask type N95 (US), Eyeshields, Gloves