S9876

Sulfathiazole

• Synonyme(s) : 4-amino-N-2-thiazolylbenzènesulfonamide
• Formule empirique (notation de Hill) : C₉H₉N₃O₂S₂
• CAS Number: 72-14-0
• Poids moléculaire : 255.32
• Beilstein: 226178
• Numéro CE : 200-771-5
• Numéro MDL: MFCD00005319
• Code UNSPSC : 41116107
• ID de substance PubChem : 329824636
• Nomenclature NACRES : NA.24

Propriétés

• Qualité: analytical standard
• Niveau de qualité: 100
• Agence: EPA 1694
• Forme: powder
• Technique(s): HPLC: suitable; gas chromatography (GC): suitable
• Pf: 200-202 °C (lit.)
• Application(s): clinical testing
• Chaîne SMILES: Nc1ccc(cc1)S(=O)(=O)Nc2nccs2
• InChI: 1S/C9H9N3O2S2/c10-7-1-3-8(4-2-7)16(13,14)12-9-11-5-6-15-9/h1-6H,10H2,(H,11,12)
• Clé InChI: JNMRHUJNCSQMMB-UHFFFAOYSA-N

Description

Description générale

Sulfathiazole is a broad-spectrum antibacterial drug, belonging to the class of sulfonamides, used in veterinary and human medication for the treatment of infections. It is also involved in promoting growth of livestock and fish.

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Sulfathiazole is used as an analytical reference standard for the quantification of the analyte in meat, and honey samples using different chromatography techniques.

Actions biochimiques/physiologiques

Sulfonamide antibiotic that blocks the synthesis of dihydrofolic acid by inhibiting the enzyme dihydropteroate synthase.
Mode of Action: Inhibits folic acid synthesis in prokaryotes.
Anti-microbial Spectrum: Gram positive, Gram negative, Chlamydia
Mode of Resistance: Alteration of dihydropteroate synthase or alternative pathway for folic acid synthesis.

Informations sur la sécurité

• Pictogrammes: GHS07
• Mention d'avertissement: Warning
• Mentions de danger: H315,H319,H335,H412
• Conseils de prudence: P261 - P264 - P271 - P273 - P302 + P352 - P305 + P351 + P338
• Classification des risques: Aquatic Chronic 3 - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Organes cibles: Respiratory system
• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 2
• Équipement de protection individuelle: dust mask type N95 (US), Eyeshields, Gloves