S1878

Sodium (meta)periodate

≥99.0%

• Synonyme(s) : Sodium periodate
• Formule linéaire : NaIO₄
• CAS Number: 7790-28-5
• Poids moléculaire : 213.89
• Numéro CE : 232-197-6
• Numéro MDL: MFCD00003534
• Code UNSPSC : 12352302
• ID de substance PubChem : 329824494
• Nomenclature NACRES : NA.55

Propriétés

• Niveau de qualité: 300
• Essai: ≥99.0%
• Forme: powder
• Pertinence de la réaction: reagent type: oxidant
• pH: 3.5-5.5 (25 °C, 107 g/L)
• Solubilité: H₂O: 50 mg/mL
• Chaîne SMILES: [Na+].[O-]I(=O)(=O)=O
• InChI: 1S/HIO4.Na/c2-1(3,4)5;/h(H,2,3,4,5);/q;+1/p-1
• Clé InChI: JQWHASGSAFIOCM-UHFFFAOYSA-M

Description

Description générale

Sodium (meta)periodate is commonly used as an oxidizing agent in organic synthesis for the oxidation of various organic substrates. It can also be used as a co-oxidant with other oxidizing reagents such as osmium tetroxide and potassium permanganate. The oxidation of sodium periodate takes place in a water medium, but an organic co-solvent is used for organic substrates that are insoluble in water.

Application

Sodium (meta)periodate can be used as an oxidizing agent for the oxidation of:      

• 1,2-diols to aldehydes or ketones via oxidative cleavage.       Sulfides to sulfoxides in the presence of phase transfer catalysts.      
• Diaryl, dialkyl, and aryl alkyl selenides to the respective selenoxides.      
• Phenols and their derivatives to corresponding quinones.
• Acylphosphoranes to α,β-dicarbonyl compounds.

It can also be used in the:      

• Selective alkene epoxidation and alkane hydroxylation,·
• Oxidation of carbohydrates.      
• Iodination of aromatic compounds.

Useful reagent for the oxidation of carbohydrates prior to labeling with biotin hydrazide

Caractéristiques et avantages

NaIO₄ is a stable, selective, and cost-effective reagent that is capable of reacting under mild conditions.

Informations sur la sécurité

• Pictogrammes: GHS03,GHS08,GHS05,GHS09
• Mention d'avertissement: Danger
• Mentions de danger: H271,H314,H372,H410
• Conseils de prudence: P210 - P260 - P273 - P280 - P303 + P361 + P353 - P305 + P351 + P338
• Classification des risques: Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1 - Ox. Sol. 1 - Skin Corr. 1C - STOT RE 1
• Organes cibles: Thyroid
• Code de la classe de stockage: 5.1A - Strongly oxidizing hazardous materials
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable