04476

Hordenine

≥97.0% (HPLC)

• Synonyme(s) : 2-(4-Hydroxyphenyl)-N,N-dimethylethylamine, 4-(2-Dimethylaminoethyl)phenol, N,N-Dimethyltyramine, p-Hydroxy-N,N-dimethylphenethylamine, Anhaline, Cactine, Eremursin, Peyocactine
• Formule empirique (notation de Hill) : C₁₀H₁₅NO
• CAS Number: 539-15-1
• Poids moléculaire : 165.23
• Beilstein: 2207615
• Numéro CE : 208-710-4
• Numéro MDL: MFCD00051462
• Code UNSPSC : 41116107
• ID de substance PubChem : 329747931
• Nomenclature NACRES : NA.25

Propriétés

• Niveau de qualité: 100
• Essai: ≥97.0% (HPLC)
• Forme: powder or crystals
• Application(s): metabolomics; vitamins, nutraceuticals, and natural products
• Chaîne SMILES: CN(C)CCc1ccc(O)cc1; CN(C)CCc1ccc(O)cc1
• InChI: 1S/C10H15NO/c1-11(2)8-7-9-3-5-10(12)6-4-9/h3-6,12H,7-8H2,1-2H3
• Clé InChI: KUBCEEMXQZUPDQ-UHFFFAOYSA-N

Description

Application

Hordenine is suitable to study the effect of reed canary grass alkoloids on in vito digestibility. It is also suitable for use as a standard to identify endogenous hordenine in ungerminated and germinated barley by HPLC/diode array detection analysis. Hordenine may be used as an analytical reference material and in research on the activities of phenethylamine type alkaloids.

Actions biochimiques/physiologiques

Hordenine is an alkaloid found in plants, e.g. the roots of germinating barley and marine algae. It is a metabolite in tyrosine metabolism, biosynthesized from tyramine by two subsequent N-methylations, it is metabolized by monoamine oxidase. Hordenine is a sympathomimetic and its pharmacological actions are of interest, as it is occasionally found in post race urine samples. Hordenine inhibits melanogenesis by suppression of cyclic adenosine monophosphate (cAMP) production. cAMP is involved in the expression of melanogenesis-related proteins. Hordenine may be used in the inhibition of hyperpigmentation. It is present in barley roots from the first day of seed germination, but is not present in seeds.

Conditionnement

Bottomless glass bottle. Contents are inside inserted fused cone.

Informations sur la sécurité

• Pictogrammes: GHS07
• Mention d'avertissement: Warning
• Mentions de danger: H315,H319,H335
• Conseils de prudence: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Classification des risques: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Organes cibles: Respiratory system
• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable