42602

Propionyl-L-carnitine

≥94.0% (HPLC), suitable for LC/MS

• Synonyme(s) : (2R)-3-Carboxy-N,N,N-trimethyl-2-(1-oxopropoxy)-1-propanaminium inner salt, L-Carnitine propionyl ester, C3-Carnitine, Propanoyl-L-carnitine
• Formule empirique (notation de Hill) : C₁₀H₁₉NO₄
• CAS Number: 20064-19-1
• Poids moléculaire : 217.26
• Numéro MDL: MFCD00870024
• Code UNSPSC : 12352209
• ID de substance PubChem : 329756246
• Nomenclature NACRES : NA.26

Propriétés

• Product Name: Propionyl-L-carnitine, ≥94.0% (HPLC)
• Niveau de qualité: 100
• Essai: ≥94.0% (HPLC)
• Forme: powder or crystals
• Activité optique: [α]/D -23±3°, c = 1 in H₂O
• Technique(s): LC/MS: suitable
• Impuretés: ≤10% water (calcd. from elemental analysis)
• Couleur: white to off-white
• Température de stockage: 2-8°C
• Chaîne SMILES: [O-]C(C[C@@H](OC(CC)=O)C[N+](C)(C)C)=O
• InChI: 1S/C10H19NO4/c1-5-10(14)15-8(6-9(12)13)7-11(2,3)4/h8H,5-7H2,1-4H3/t8-/m1/s1
• Clé InChI: UFAHZIUFPNSHSL-MRVPVSSYSA-N

Description

Description générale

Propionyl-L-carnitine (PLC) is a short-chain fatty acid ester derivative of carnitine.

Application

Propionyl-L-carnitine has been used as a standard in liquid chromatography-tandem mass spectrometry (LC-MS/MS).

Actions biochimiques/physiologiques

Propionyl-L-carnitine (PLC) plays a key role in lipid and carbohydrate metabolism. It provides substrates to the ischemic muscle for energy production and ATP generation. PLC has the potential to treat severe peripheral arterial disease and chronic heart failure. It is present in high abundance in the urine of patients with methylmalonyl-CoA mutase (MUT) deficiency, together with methylmalonic acid. MUT is a mitochondrial enzyme that catalyzes the isomerization of methylmalonyl-CoA to succinyl-CoA.

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable