86614

Tetraethylammonium chloride

BioUltra, Molecular Biology, ≥99.0% (AT)

• Synonyme(s) : Etamon chloride, TEAC, TEA chloride
• Formule linéaire : (C₂H₅)₄N(Cl)
• CAS Number: 56-34-8
• Poids moléculaire : 165.70
• Beilstein: 3563247
• Numéro CE : 200-267-5
• Numéro MDL: MFCD00011828
• Code UNSPSC : 12352107
• ID de substance PubChem : 57653171
• Nomenclature NACRES : NA.26

Propriétés

• Qualité: Molecular Biology
• Niveau de qualité: 100
• Gamme de produits: BioUltra
• Essai: ≥99.0% (AT)
• Forme: powder
• Poids mol.: 165.70 g/mol
• Technique(s): gas chromatography (GC): suitable
• Impuretés: DNases, none detected; RNases, none detected; insoluble matter, passes filter test; phosphatases, none detected; proteases, none detected
• Solubilité: H₂O: 1 M at 20 °C, clear, colorless
• Traces d'anions: bromide (Br^-): ≤500 mg/kg; sulfate (SO₄^2-): ≤50 mg/kg
• Traces de cations: Al: ≤5 mg/kg; As: ≤0.1 mg/kg; Ba: ≤5 mg/kg; Bi: ≤5 mg/kg; Ca: ≤10 mg/kg; Cd: ≤5 mg/kg; Co: ≤5 mg/kg; Cr: ≤5 mg/kg; Cu: ≤5 mg/kg; Fe: ≤5 mg/kg; K: ≤50 mg/kg; Li: ≤5 mg/kg; Mg: ≤5 mg/kg; Mn: ≤5 mg/kg; Mo: ≤5 mg/kg; Na: ≤50 mg/kg; Ni: ≤5 mg/kg; Pb: ≤5 mg/kg; Sr: ≤5 mg/kg; Zn: ≤5 mg/kg
• λ: 1 M in H₂O
• Absorption UV: λ: 260 nm A_max: 0.03; λ: 280 nm A_max: 0.03
• Chaîne SMILES: [Cl-].CC[N+](CC)(CC)CC
• InChI: 1S/C8H20N.ClH/c1-5-9(6-2,7-3)8-4;/h5-8H2,1-4H3;1H/q+1;/p-1
• Clé InChI: YMBCJWGVCUEGHA-UHFFFAOYSA-M

Description

Description générale

Tetraethylammonium (TEA), a simple quaternary ammonium compound, is commonly used to block potassium channels. It can physically enter the pore and block the channel. Additionally, TEA either imitates or antagonizes the actions of choline and acetylcholine, two other quaternary ammonium ions.

Application

Tetraethylammonium chloride has been used:

• as a pharmacological agent in electrophysiology to study its pharmacological effects on Cnidarians
• as a component in refolding buffer for protein refolding
• to puff onto isolated patches to block voltage-gated K⁺ (Kv3) channels and post-hoc evaluation

Caractéristiques et avantages

• Assay: ≥99.0% (AT), BioUltra, for molecular biology
• Suitable for gas chromatography (GC)

Autres remarques

TEACl method of DNA-DNA hybridization

Informations sur la sécurité

• Pictogrammes: GHS07
• Mention d'avertissement: Warning
• Mentions de danger: H315,H319
• Conseils de prudence: P264 - P280 - P302 + P352 - P305 + P351 + P338 - P332 + P313 - P337 + P313
• Classification des risques: Eye Irrit. 2 - Skin Irrit. 2
• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): 201.2 °F - closed cup
• Point d'éclair (°C): 94 °C - closed cup
• Équipement de protection individuelle: dust mask type N95 (US), Eyeshields, Gloves