A0550

Ala-Gln

≥98% (HPLC)

• Synonyme(s) : Alanyl-glutamine, Glutamine-S
• Formule empirique (notation de Hill) : C₈H₁₅N₃O₄
• CAS Number: 39537-23-0
• Poids moléculaire : 217.22
• Numéro MDL: MFCD00133046
• Code UNSPSC : 12352209
• ID de substance PubChem : 24890433
• Nomenclature NACRES : NA.26

Propriétés

• Product Name: Ala-Gln, ≥98% (HPLC)
• Niveau de qualité: 200
• Essai: ≥98% (HPLC)
• Forme: powder
• Couleur: white to off-white
• Chaîne SMILES: NC(CC[C@H](NC([C@@H](N)C)=O)C(O)=O)=O
• InChI: 1S/C8H15N3O4/c1-4(9)7(13)11-5(8(14)15)2-3-6(10)12/h4-5H,2-3,9H2,1H3,(H2,10,12)(H,11,13)(H,14,15)/t4-,5-/m0/s1
• Clé InChI: HJCMDXDYPOUFDY-WHFBIAKZSA-N

Description

Application

L-Glutamine is an essential supplement for cell culture. The free amino acid L-glutamine is unstable and degrades to pyroglutamate. Alanyl-L-glutamine (Ala-Gln) and Gylcyl-L-glutamine (Gly-Gln) are used in cell culture as alternative delivery forms of stabilized L-glutamine. The primary advantage of using L-alanylglutamine in place of L-glutamine is that it reduces the level of ammonia generated during cell culture.

Actions biochimiques/physiologiques

Alanyl-glutamine is a widely used alternative supplement to L-glutamine in the production of biopharmaceuticals. Alanyl-glutamine also acts as an antioxidant (peroxide) and anti-apoptosis (LPS-induced) factor. Ala-Gln has been used in studies on injury and sepsis, and on the effects of irradiation on leucine and protein metabolism in vivo. Ala-Gln has been utilized to investigate polymorphonuclear leucocyte and myeloperoxidase activity in vitro.

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 1
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable
• Équipement de protection individuelle: Eyeshields, Gloves, type N95 (US)