A1752

Adenosine 5′-monophosphate sodium salt

from yeast, ≥99%

• Synonyme(s) : 5′-Adenylic acid, A-5′-P, AMP
• Formule empirique (notation de Hill) : C₁₀H₁₄N₅O₇P · xNa⁺ · yH₂O
• CAS Number: 149022-20-8
• Poids moléculaire : 347.22 (anhydrous free acid basis)
• Numéro MDL: MFCD08689634
• Code UNSPSC : 41106305
• eCl@ss : 32160414
• ID de substance PubChem : 24890583
• Nomenclature NACRES : NA.51

Propriétés

• Source biologique: yeast
• Niveau de qualité: 300
• Essai: ≥99%
• Forme: powder
• Solubilité: H₂O: soluble
• Température de stockage: −20°C
• Chaîne SMILES: NC1=NC=NC2=C1N=CN2[C@H]3[C@H](O)[C@H](O)[C@]((COP(O)(O)=O)([H])O3.C.

Description

Application

Adenosine 5′-monophosphate sodium salt has been used:

• as a component of reactivation medium to reactivate mouse sperm extracted from caudae epididymides for sperm motility studies
• as a substrate in signal amplification by reversible exchange (SABRE) method to develop biocompatible SABRE hyperpolarization
• as a substrate in wheat and Aspergillus niger phytase, assay
• in luciferase assay to monitor intracellular α-synuclein oligomerization in S1S2 cells
• to study its effects on induction of therapeutic hypothermia and neuronal damage in a rat model of cardiac arrest (CA) and resuscitation

Actions biochimiques/physiologiques

Adenosine 5′-monophosphate (5′-AMP) is used to enhance flavor in meat and poultry soups. It is also used as a food additive for specific nutritional purposes. 5′-AMP is an activator of a class of protein kinases known as AMP-activated protein kinase (AMPK). Along with inosine monophosphate (IMP), AMP mediates the dissociation of skeletal muscle actomyosin to actin and myosin. Therefore, these two factors may be involved in causing the resolution of rigor mortis in muscles.

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable
• Équipement de protection individuelle: Eyeshields, Gloves, type N95 (US)