A4034

Lascorbate de (+)-sodium

powder, BioReagent, suitable for cell culture

• Synonyme(s) : Acide L(+)-ascorbique sodium salt, Vitamine C sodium salt
• Formule empirique (notation de Hill) : C₆H₇NaO₆
• CAS Number: 134-03-2
• Poids moléculaire : 198.11
• Beilstein: 3767246
• Numéro CE : 205-126-1
• Numéro MDL: MFCD00082340
• Code UNSPSC : 12352205
• eCl@ss : 34058010
• ID de substance PubChem : 24890738
• Nomenclature NACRES : NA.75

Propriétés

• Source biologique: synthetic (organic)
• Gamme de produits: BioReagent
• Essai: ≥98%
• Forme: powder
• Poids mol.: M_w 135.13 g/mol
• Technique(s): cell culture | mammalian: suitable; cell culture | plant: suitable
• Couleur: white to off-white
• Pf: 220 °C (dec.) (lit.)
• Solubilité: H₂O: 50 mg/mL
• Chaîne SMILES: [Na+].OC[C@H](O)[C@H]1OC(=O)C(O)=C1[O-]
• InChI: 1S/C6H8O6.Na/c7-1-2(8)5-3(9)4(10)6(11)12-5;/h2,5,7-10H,1H2;/q;+1/p-1/t2-,5+;/m0./s1
• Clé InChI: PPASLZSBLFJQEF-RXSVEWSESA-M

Description

Description générale

(+)-Sodium L-ascorbate (SA) is a potential antioxidant and is a derivative of vitamin C (L-ascorbic acid). It is widely used as a food additive. In addition, SA enhances growth retardation activity of bleomycin sulfate, R020-1724 (an inhibitor of cyclic nucleotide phosphodiesterase), prostaglandin E1 and sodium butyrate agents on neuroblastoma cells in culture. Elevated levels of SA induces two-stage urinary bladder carcinogenesis in rats. sodium L-ascorbate in combination with collagenogenesis inhibitors is used to treat dermal scars and keloids.

Application

(+)-Sodium L-ascorbate has been used:

• to produce H₂O₂ in cell culture media
• as a reducing agent for a cell-permeable artificial electron donor, N,N,N′,N′-tetramethyl-p-phenylenediamine (TMPD)
• to study its effect on production of collagen and elastic fibers in fibroblasts cultures derived from normal human skin and dermal fat

Used for preparation of plant extracts; reductant for the isolation of chloroplasts.

Actions biochimiques/physiologiques

Antioxidant

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 1
• Équipement de protection individuelle: Eyeshields, Gloves, type N95 (US)