A7655

Atenolol

≥98% (TLC), powder, β₁-adrenoceptor antagonist

• Synonyme(s) : (±)-4-[2-Hydroxy-3-[(1-methylethyl)amino]propoxy]benzeneacetamide, 4-[2′-Hydroxy-3′-(isopropylamino)propoxy]phenylacetamide
• Formule empirique (notation de Hill) : C₁₄H₂₂N₂O₃
• CAS Number: 29122-68-7
• Poids moléculaire : 266.34
• Numéro CE : 249-451-7
• Numéro MDL: MFCD00057645
• Code UNSPSC : 12352200
• ID de substance PubChem : 24277748
• Nomenclature NACRES : NA.77

Propriétés

• Product Name: Atenolol, ≥98% (TLC), powder
• Niveau de qualité: 200
• Essai: ≥98% (TLC)
• Forme: powder
• Couleur: white to off-white
• Solubilité: H₂O: 0.3 mg/mL; DMSO: 18 mg/mL; ethanol: 3.4 mg/mL
• Auteur: AstraZeneca
• Chaîne SMILES: CC(C)NCC(O)COc1ccc(CC(N)=O)cc1
• InChI: 1S/C14H22N2O3/c1-10(2)16-8-12(17)9-19-13-5-3-11(4-6-13)7-14(15)18/h3-6,10,12,16-17H,7-9H2,1-2H3,(H2,15,18)
• Clé InChI: METKIMKYRPQLGS-UHFFFAOYSA-N
• Informations sur le gène: human ... ADRB1(153) ; rat ... Adrb1(24925)

Description

Application

Atenolol is a β-adrenergic blocker and used in the management of hypertension. Atenolol has antianginal and antiarrhythmic properties.

Actions biochimiques/physiologiques

Selective β₁-adrenoceptor antagonist; antihypertensive; antianginal; antiarrhythmic.

Caractéristiques et avantages

This compound is featured on the β-Adrenoceptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

This compound was developed by AstraZeneca. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Autres remarques

Shelf-life of the solid is at least three years.

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 2
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable
• Équipement de protection individuelle: Eyeshields, Gloves, type N95 (US)