A9732

Anti-ATP13A2 (C-terminal) antibody produced in rabbit

~1.5 mg/mL, affinity isolated antibody, buffered aqueous solution

• Synonyme(s) : Anti-ATPase type 13A2, Anti-PARK9
• Code UNSPSC : 12352203
• Nomenclature NACRES : NA.41

Propriétés

• Source biologique: rabbit
• Niveau de qualité: 200
• Conjugué: unconjugated
• Forme d'anticorps: affinity isolated antibody
• Type de produit anticorps: primary antibodies
• Clone: polyclonal
• Forme: buffered aqueous solution
• Poids mol.: antigen ~129 kDa
• Espèces réactives: mouse, human
• Validation améliorée: recombinant expression; Learn more about Antibody Enhanced Validation
• Concentration: ~1.5 mg/mL
• Technique(s): western blot: 1-2 μg/mL using mouse brain extract (S1 fraction); western blot: 2-4 μg/mL using extract of HEK-293T cells expressing human ATP13A2
• Numéro d'accès UniProt: Q9NQ11
• Conditions d'expédition: dry ice
• Température de stockage: −20°C
• Modification post-traductionnelle de la cible: unmodified
• Informations sur le gène: human ... ATP13A2(23400) ; mouse ... Atp13a2(74772)

Description

Description générale

ATP13A2 is a member of the P5 family of ATPases which function in the transport of inorganic cations.

ATPase type 13 A2 (ATP13A2), also known as Parkinson′s disease 9 (PARK9), codes for P-type ATPase that is present on the lysosomal membrane with ten transmembrane domains.

Application

Anti-ATP13A2 (C-terminal) antibody produced in rabbit has also been used in immunohistochemistry.

Rabbit Anti-ATP13A2 (C-terminal) antibody has be used for immunofluorescence and western blotting assays.

Actions biochimiques/physiologiques

ATPase type 13A2 (ATP13A2) plays a vital role in regulation of mitochondrial bioenergetics by macroautophagy. Mutations in the ATP13A2 gene leads to the development of hereditary form of Parkinson associated with dementia, known as Kufor-Rakeb syndrome (KRS).

Forme physique

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informations sur la sécurité

• Code de la classe de stockage: 10 - Combustible liquids
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable
• Équipement de protection individuelle: Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)