B2680

BMP4, human

>95% (SDS-PAGE), recombinant, expressed in NSO cells, lyophilized powder, suitable for cell culture

• Synonyme(s) : Bone Morphogenetic Protein 4 human, BMP-4
• Numéro MDL: MFCD01867024
• Code UNSPSC : 12352202
• Nomenclature NACRES : NA.32

Propriétés

• Product Name: Bone Morphogenetic Protein 4 human, >95% (SDS-PAGE), recombinant, expressed in NSO cells, lyophilized powder, suitable for cell culture
• Source biologique: human
• Niveau de qualité: 200
• Produit recombinant: expressed in NSO cells
• Essai: >95% (SDS-PAGE)
• Forme: lyophilized powder
• Puissance: 10-30 ng/mL ED₅₀
• Poids mol.: monomer calculated mol wt 13 kDa; ~22 kDa by SDS-PAGE
• Conditionnement: pkg of 10 μg
• Conditions de stockage: avoid repeated freeze/thaw cycles (Do not store in a frost-free freezer.)
• Technique(s): cell culture | mammalian: suitable
• Impuretés: <1 EU/mg Endotoxin level (LAL test)
• Numéro d'accès UniProt: P12644
• Température de stockage: −20°C
• Informations sur le gène: human ... BMP4(652)

Description

Actions biochimiques/physiologiques

Cellular responses to BMP-4 are mediated by the formation of hetero-oligomeric complexes of type I and type II serine/threonine kinase receptors. BMPs stimulate angiogenesis by inducing the production of VEGF A by osteoblasts. Mature human and mouse BMP-4 demonstrates 98% and 100% homology, respectively, to mature rat BMP-4.

Forme physique

Lyophilized from a 0.2 μm filtered solution in 30% acetonitrile and 0.1% trifluoroacetic acid containing 50 μg of bovine serum albumin per 1 μg of cytokine.

Remarque sur l'analyse

The biological activity is measured by its ability to induce alkaline phosphatase production by C2C12 myoblasts.

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable