B2929

B-Lymphocyte Chemoattractant human

≥95% (SDS-PAGE), recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture

• Synonyme(s) : B-Cell Attracting Chemokine 1, BCA-1, BLC
• Numéro MDL: MFCD01867020
• Code UNSPSC : 12352202
• Nomenclature NACRES : NA.32

Propriétés

• Source biologique: human
• Niveau de qualité: 200
• Produit recombinant: expressed in E. coli
• Essai: ≥95% (SDS-PAGE)
• Forme: lyophilized powder
• Puissance: 0.1000 μg/mL
• Poids mol.: apparent mol wt 8.7 kDa by SDS-PAGE (reducing)
• Conditionnement: pkg of 25 μg
• Conditions de stockage: avoid repeated freeze/thaw cycles (Do not store in a frost-free freezer.)
• Technique(s): cell culture | mammalian: suitable
• Impuretés: endotoxin, tested
• Numéro d'accès UniProt: O43927
• Température de stockage: −20°C
• Informations sur le gène: human ... CXCL13(10563)

Description

Actions biochimiques/physiologiques

BCA-1 is a potent chemoattractant for B lymphocytes, but not T lymphocytes, monocytes, or neutrophils.

BCA-1 is a potent chemoattractant for B lymphocytes, but not T lymphocytes, monocytes, or neutrophils. Its specific receptor BLR1 is a G protein-coupled receptor originally isolated from Burkitt′s lymphoma cells. Among cells of the hematopoietic lineages, the expression of BRL1, now designated CXCR5, is restricted to B lymphocytes and a subpopulation of T helper memory cells.

Potent chemoattractant for B lymphocytes, but not T lymphocytes, monocytes, or neutrophils.

The biological activity of human BLC/BCA-1 is measured by its ability to chemoattract mouse BaF/3 cells transfected with human CXCR5.

Forme physique

Lyophilized from a 0.2 μm filtered solution in 35% acetonitrile and 0.1% TFA containing 50 μg bovine serum albumin per 1 μg of cytokine.

Informations sur la sécurité

• Pictogrammes: GHS07
• Mention d'avertissement: Warning
• Mentions de danger: H302 + H332,H319
• Conseils de prudence: P261 - P264 - P270 - P301 + P312 - P304 + P340 + P312 - P305 + P351 + P338
• Classification des risques: Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2
• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable