B9636

S-Benzoylthiamine O-monophosphate

• Synonyme(s) : Benfotiamine
• Formule empirique (notation de Hill) : C₁₉H₂₃N₄O₆PS
• CAS Number: 22457-89-2
• Poids moléculaire : 466.45
• Numéro CE : 245-013-4
• Numéro MDL: MFCD00057343
• Code UNSPSC : 12352116
• ID de substance PubChem : 24892147
• Nomenclature NACRES : NA.79

Propriétés

• Essai: ≥98% (TLC)
• Niveau de qualité: 200
• Forme: powder or crystals
• Couleur: white to off-white
• Température de stockage: 2-8°C
• Chaîne SMILES: Cc1ncc(CN(C=O)\C(C)=C(/CCOP(O)(O)=O)SC(=O)c2ccccc2)c(N)n1
• InChI: 1S/C19H23N4O6PS/c1-13(23(12-24)11-16-10-21-14(2)22-18(16)20)17(8-9-29-30(26,27)28)31-19(25)15-6-4-3-5-7-15/h3-7,10,12H,8-9,11H2,1-2H3,(H2,20,21,22)(H2,26,27,28)/b17-13+
• Clé InChI: BTNNPSLJPBRMLZ-GHRIWEEISA-N

Description

Description générale

S-Benzoylthiamine O-monophosphate (Benfotiamine) is an amphiphilic S-acyl thiamine derivative. It is a lipid-soluble vitamin. Benfotiamine contains a thiazole ring. Benfotiamine has a greater bioavailability than thiamine.

Application

S-Benzoylthiamine O-monophosphate has been used to determine its effect on ischemia and reperfusion in skeletal muscles of rat.

Actions biochimiques/physiologiques

S-Benzoylthiamine O-monophosphate (Benfotiamine) is a therapeutic agent. It helps in the prevention of diabetic complications such as, retinopathy, neuropathy and nephropathy. Benfotiamine inhibits the synthesis of glycation end products (AGEs) in diabetes. Benfotiamine is considered as a nutraceutical product for the prevention of diabetic neuropathy.

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 2
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable
• Équipement de protection individuelle: Eyeshields, Gloves, type N95 (US)