C1688

Anti-C-Reactive Protein antibody, Mouse monoclonal

clone CRP-8, purified from hybridoma cell culture

• Synonyme(s) : Monoclonal Anti-C-Reactive Protein antibody produced in mouse, Anti-CRP
• Numéro MDL: MFCD00162183
• Code UNSPSC : 12352203
• Nomenclature NACRES : NA.41

Propriétés

• Source biologique: mouse
• Niveau de qualité: 200
• Conjugué: unconjugated
• Forme d'anticorps: ascites fluid
• Type de produit anticorps: primary antibodies
• Clone: CRP-8, monoclonal
• Poids mol.: antigen 24 kDa
• Contient: 15 mM sodium azide
• Espèces réactives: human
• Technique(s): dot blot: suitable; indirect ELISA: 1:40,000; western blot: 1:200
• Isotype: IgG1
• Numéro d'accès UniProt: P02741
• Conditions d'expédition: dry ice
• Température de stockage: −20°C
• Modification post-traductionnelle de la cible: unmodified
• Informations sur le gène: human ... CRP(1401)

Description

Description générale

C-reactive protein (CRP) is a member of the pentraxin family of proteins and synthesized by the liver. It is also known as PTX1. The CRP gene is mapped to human chromosome 1q23.2.

Spécificité

The antibody recognizes an epitope located on the 24 kDa subunit of denatured and reduced CRP. It does not cross-react with human serum amyloid P component (SAP), human haptoglobin, human α₁-acid glycoprotein, human IgG, and CRP from Limulus.

Immunogène

human C-reactive protein.

Application

• It has been used in immunoblotting assay, to identify monomeric CRP.
• In time-resolved fluorometric assay.

Monoclonal Anti-C-Reactive Protein antibody produced in mouse is suitable for the following:

• dot blot analysis
• indirect ELISA at a working dilution of 1:40,000
• western blotting at a working dilution of 1:200

Actions biochimiques/physiologiques

C-reactive protein (CRP) shows essential scavenging and metabolic activity and is also associated with defence mechanism. It activates the complement pathway by binding to calcium-dependent exogenous and autologous molecules containing phosphocholine (PC). It may have pathogenic effects and is a practical prognostic marker in patients with hepatocellular carcinoma (HCC). The CRP diagnostic value is higher for acute pyelonephritis than lower urinary tract infection. Thus, it helps in differentiating between upper and lower urinary tract infection. It is considered best for predicting the risk of cardiovascular disease..

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informations sur la sécurité

• Code de la classe de stockage: 12 - Non Combustible Liquids
• Classe de danger pour l'eau (WGK): WGK 1
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable