C2196

L-Cysteine S-sulfate

≥98% (TLC), suitable for ligand binding assays

• Synonyme(s) : S-Sulfo-L-cysteine
• Formule empirique (notation de Hill) : C₃H₇NO₅S₂
• CAS Number: 1637-71-4
• Poids moléculaire : 201.22
• Beilstein: 1726832
• Numéro MDL: MFCD00133440
• Code UNSPSC : 12352209
• ID de substance PubChem : 24892471
• Nomenclature NACRES : NA.26

Propriétés

• Product Name: L-Cysteine S-sulfate, ≥98% (TLC)
• Niveau de qualité: 200
• Essai: ≥98% (TLC)
• Forme: powder
• Technique(s): ligand binding assay: suitable
• Couleur: white
• Température de stockage: −20°C
• Chaîne SMILES: N[C@@H](CSS(O)(=O)=O)C(O)=O
• InChI: 1S/C3H7NO5S2/c4-2(3(5)6)1-10-11(7,8)9/h2H,1,4H2,(H,5,6)(H,7,8,9)/t2-/m0/s1
• Clé InChI: NOKPBJYHPHHWAN-REOHCLBHSA-N

Description

Actions biochimiques/physiologiques

L-Cysteine S-sulfate (LCSS) is used as an NMDA glutamatergic receptor agonist. It serves as a substrate for cystine lyase(s).
Cysteine is one of the functional amino acids that are associated with growth, reproduction, maintenance and immunity. Cysteine is a source of disulfide linkage in protein and is associated with sulfur transport. At physiological pH, cysteine undergoes rapid oxidation to form cystine. Reduced availability of cysteine or cystine, influences leukocyte metabolism. L-Cysteine serves as a precursor for the rate limiting step in glutathione synthesis that occurs in neurons. It donates inorganic sulfate for detoxification reactions. Therefore, L-cysteine might be associated with neuroprotection. It is found to obstruct the entry of heavy metal ions across the blood-brain barrier into the brain. Increased levels of L-cysteine might lead to neurotoxicity.

Informations sur la sécurité

• Pictogrammes: GHS07
• Mention d'avertissement: Warning
• Mentions de danger: H315,H319,H335
• Conseils de prudence: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Classification des risques: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Organes cibles: Respiratory system
• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable
• Équipement de protection individuelle: dust mask type N95 (US), Eyeshields, Gloves