C5424

Conduritol B epoxide

powder, ≥95% (TLC)

• Synonyme(s) : 1,2-Anhydro-myo-inositol
• CAS Number: 6090-95-5
• Numéro MDL: MFCD00077326
• Code UNSPSC : 12352119
• ID de substance PubChem : 24892783
• Nomenclature NACRES : NA.32

Propriétés

• Product Name: Conduritol B epoxide,
• Source biologique: synthetic (organic)
• Niveau de qualité: 100
• Essai: ≥95% (TLC)
• Forme: powder
• Solubilité: water: 20 mg/mL, clear, colorless to faintly yellow
• Température de stockage: 2-8°C
• Chaîne SMILES: OC1C(O)C(O)C2OC2C1O
• InChI: 1S/C6H10O5/c7-1-2(8)4(10)6-5(11-6)3(1)9/h1-10H
• Clé InChI: ZHMWOVGZCINIHW-UHFFFAOYSA-N

Description

Description générale

Conduritol B epoxide (CBE) is a mix of 1-L-1,2-anhydro-myo-inositol and 1-D-1,2-anhydro-myo-inositol.

Application

Conduritol B epoxide has been used as an inhibitor of GBA1 to discriminate between acid β-glucosidase (GBA1) and non-lysosomal β-glucosidase (GBA2) activity in β-glucosidase activity assay. It has also been used as a selective glucocerebrosidase (GCase) inhibitor.

Actions biochimiques/physiologiques

β-Glucosidase inhibitor

Conduritol B epoxide (CBE) is capable of inactivating sucrase-isomaltase irreversibly. It can be used to produce cell and animal models to study on Gaucher disease (GD) and Parkinson′s disease (PD).

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable
• Équipement de protection individuelle: Eyeshields, Gloves, type N95 (US)