C5608

Collagen from rabbit skin

Bornstein and Traub Type I, powder

• CAS Number: 9007-34-5
• Numéro CE : 232-697-4
• Numéro MDL: MFCD00130825
• Code UNSPSC : 12352202
• Nomenclature NACRES : NA.61

Propriétés

• Source biologique: rabbit skin
• Niveau de qualité: 200
• Description: acid soluble
• Forme: powder
• Technique(s): cell culture | stem cell: suitable
• Solubilité: aqueous acid: ≤10 mg/mL; aqueous sodium acetate buffer: soluble (0.01-0.5M)
• Numéro d'accès UniProt: Q28668
• Température de stockage: 2-8°C
• Informations sur le gène: rabbit ... COL1A2(100008997)

Description

Description générale

Collagen is classified into a number of structurally and genetically distinct types. We use the nomenclature proposed by Bornstein and Traub. Do not confuse Sigma type designations with recognized collagen classification types.

Application

Collagen-type 1 may be used in research of Idiopathic pulmonary fibrosis (IPF). Robust expression of collagen-type 1 is one distinctive feature of IPF. Additionally, collagen-type 1 has been used in studies on the effect of endoplasmic reticulum (ER) stress from IPF on myofibroblastic differentiation of lung fibroblasts. Collage-type 1 soluble in acidic solution produces three dimensional scaffolding useful in bioengineering and cell culture applications where biomaterials are needed to replace native collagen extracellular matrices.

Collagen Type I has been used as a scaffold for the growth in vitro of stem cells in a wide variety of biomaterial engineering studies.

Notes préparatoires

Prepared with modification of Gallop, P.M.

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 1
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable
• Équipement de protection individuelle: Eyeshields, Gloves, type N95 (US)