D2773

Dithranol

≥90% (HPLC)

• Synonyme(s) : 1,8,9-Anthracenetriol, 1,8-Dihydroxy-9(10H)-anthracenone, 1,8-Dihydroxyanthrone, Anthralin
• Formule empirique (notation de Hill) : C₁₄H₁₀O₃
• CAS Number: 1143-38-0
• Poids moléculaire : 226.23
• Beilstein: 2054360
• Numéro CE : 214-538-0
• Numéro MDL: MFCD00053409
• Code UNSPSC : 12352201
• ID de substance PubChem : 24893712
• Nomenclature NACRES : NA.25

Propriétés

• Niveau de qualité: 200
• Essai: ≥90% (HPLC)
• Forme: solid
• Pf: 178-181 °C (lit.)
• Solubilité: chloroform: 20 mg/mL, clear to very slightly hazy, yellow
• Chaîne SMILES: Oc1cccc2Cc3cccc(O)c3C(=O)c12
• InChI: 1S/C14H10O3/c15-10-5-1-3-8-7-9-4-2-6-11(16)13(9)14(17)12(8)10/h1-6,15-16H,7H2
• Clé InChI: NUZWLKWWNNJHPT-UHFFFAOYSA-N
• Informations sur le gène: mouse ... Alox12(11684)

Description

Description générale

Dithranol (1, 8 - dihydroxy-9-anthrone) is also called as anthralin. It is a vital topical antipsoriatic drugs. Dithranol, an athracene derivative, is a free radical generating mitochondrial poison that induces apoptosis in keratinocytes.

Application

Dithranol, a potential anti-psoriasis medication, may be used to study its safety, efficacy, metabolism and pharmacological profile. Dithranol may be used to study is physicochemical properties, as a reference compound and to develop effective drug delivery vehicles. Dithranol may be used as a matrix for matrix assisted laser desorption/ionization imaging on a Fourier transform ion cyclotron resonance mass spectrometer.

Autres remarques

To gain a comprehensive understanding of our extensive range of Polysaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Informations sur la sécurité

• Pictogrammes: GHS07
• Mention d'avertissement: Warning
• Mentions de danger: H315,H319,H335
• Conseils de prudence: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Classification des risques: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Organes cibles: Respiratory system
• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable
• Équipement de protection individuelle: dust mask type N95 (US), Eyeshields, Gloves