D3168

Duramycin from Streptoverticillium cinnamoneus

≥90.0%

• Synonyme(s) : Duramycin, Lancovutide
• Formule empirique (notation de Hill) : C₈₉H₁₂₅N₂₃O₂₅S₃
• CAS Number: 1391-36-2
• Poids moléculaire : 2013.28
• Numéro MDL: MFCD00133301
• Code UNSPSC : 51102829
• Nomenclature NACRES : NA.85

Propriétés

• Niveau de qualité: 200
• Essai: ≥90.0%
• Forme: powder
• Solubilité: 0.1 M HCl: 10 mg/mL
• Spectre d'activité de l'antibiotique: Gram-negative bacteria; Gram-positive bacteria
• Mode d’action: protein synthesis | interferes
• Température de stockage: 2-8°C

Description

Description générale

Chemical structure: tetracycline

Application

Duramycin is used to study chloride secretion by cardial, pancreatic and airway epithelial voltage-gated ion channels. It is used to study cystic fibrosis and as a novel phosphatidylethanolamine-binding molecular probe. It is used to stimulate sodium transport in cultured human colonic epithelia.

Actions biochimiques/physiologiques

Duramycin is the smallest known polypeptide since it has only 19 amino acids. It has a defined 3-dimensional binding structure. Duramycin binds phosphatidylethanolamine (PtdE) at a 1:1 ratio with high affinity and exclusive specificity. It enhances chloride secretion in airway epithelium.

Autres remarques

Keep container tightly closed in a dry and well-ventilated place.

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable
• Équipement de protection individuelle: Eyeshields, Gloves, type N95 (US)