D5564

7,8-Dihydroxycoumarin

≥97%, powder

• Synonyme(s) : Daphnetin, Daphnetol, Ruixiangsu
• Formule empirique (notation de Hill) : C₉H₆O₄
• CAS Number: 486-35-1
• Poids moléculaire : 178.14
• Numéro CE : 207-632-8
• Numéro MDL: MFCD00016977
• Code UNSPSC : 12352200
• ID de substance PubChem : 24278375
• Nomenclature NACRES : NA.77

Propriétés

• Source biologique: synthetic (organic)
• Niveau de qualité: 200
• Essai: ≥97%
• Forme: powder
• Solubilité: ethanol: 5 mg/mL
• Température de stockage: room temp
• Chaîne SMILES: Oc1ccc2C=CC(=O)Oc2c1O
• InChI: 1S/C9H6O4/c10-6-3-1-5-2-4-7(11)13-9(5)8(6)12/h1-4,10,12H
• Clé InChI: ATEFPOUAMCWAQS-UHFFFAOYSA-N

Description

Actions biochimiques/physiologiques

7,8-Dihydroxycoumarinan is an inhibitor of protein kinases. It is an active lactone present in plants such as Daphne Korean Nakai, and Thymelaeaceae Daphne. It serves as as analgesic, antiviral and antibacterial agent. 7,8-Dihydroxycoumarinan is found to induce tumor apoptosis via a number of signalling pathways. Thus, it is believed to exhibit antitumor effects. 7,8-Dihydroxycoumarinan might also be useful in treating lung carcinoma. It is also known to be used in treating coagulation disorders and rheumatoid arthritis. 7,8-Dihydroxycoumarinan is known to induce neurite growth and lengthen neuronal survival. It helps in clearing substances inducing necrosis, maintains water-electrolytes balance and energy metabolism. 7,8-Dihydroxycoumarinan is involved in the generation of neurotrophic factor and helps in restoring neuron function.

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 2
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable
• Équipement de protection individuelle: Eyeshields, Gloves, type N95 (US)