D7571

Dimaprit dihydrochloride

≥98% (NMR)

• Synonyme(s) : Carbamimidothioic acid, 3-(dimethylamino)propyl ester, hydrochloride (1:2), Dimaprit-2HCl
• Formule empirique (notation de Hill) : C₆H₁₅N₃S · 2HCl
• CAS Number: 23256-33-9
• Poids moléculaire : 234.19
• Numéro MDL: MFCD00069260
• Code UNSPSC : 12352200
• ID de substance PubChem : 329798854
• Nomenclature NACRES : NA.77

Propriétés

• Niveau de qualité: 100
• Essai: ≥98% (NMR)
• Forme: powder
• Couleur: white to off-white
• Solubilité: H₂O: ≥50 mg/mL
• Auteur: Roche
• Température de stockage: −20°C
• Chaîne SMILES: Cl.Cl.CN(C)CCCSC(N)=N
• InChI: 1S/C6H15N3S.2ClH/c1-9(2)4-3-5-10-6(7)8;;/h3-5H2,1-2H3,(H3,7,8);2*1H
• Clé InChI: DFWCPLGXFMSUCW-UHFFFAOYSA-N

Description

Actions biochimiques/physiologiques

Selective histamine receptor H2 agonist.

The histamine H2 receptor influences various cardiovascular responses, including vasodilation and cardiac rhythm, regulates gastric acid secretion, and also plays a role in the immune system by inhibiting antibody production, T cell proliferation and cytokine production. Histamine receptors are members of the GPCR family, and H2 mediates cell signaling via internalization and interaction with the GTPase dynamin.

Caractéristiques et avantages

This compound is featured on the Histamine Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

This compound was developed by Roche. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Informations sur la sécurité

• Pictogrammes: GHS07
• Mention d'avertissement: Warning
• Mentions de danger: H315,H319,H335
• Conseils de prudence: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Classification des risques: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Organes cibles: Respiratory system
• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable