E114

EHNA hydrochloride

≥98% (HPLC), powder, adenosine deaminase inhibitor

• Synonyme(s) : erythro-9-(2-Hydroxy-3-nonyl)­adenine hydrochloride, erythro-9-Amino-β-hexyl-­α-methyl-9H-purine-9-ethanol hydrochloride
• Formule empirique (notation de Hill) : C₁₄H₂₃N₅O · HCl
• CAS Number: 58337-38-5
• Poids moléculaire : 313.83
• Numéro MDL: MFCD00151066
• Code UNSPSC : 12352200
• ID de substance PubChem : 24277713
• Nomenclature NACRES : NA.77

Propriétés

• Product Name: EHNA hydrochloride, ≥98% (HPLC)
• Niveau de qualité: 100
• Essai: ≥98% (HPLC)
• Conditions de stockage: desiccated
• Solubilité: DMSO: >10 mg/mL; H₂O: >10 mg/mL
• Chaîne SMILES: Cl[H].CCCCCC[C@H]([C@H](C)O)n1cnc2c(N)ncnc12
• InChI: 1S/C14H23N5O.ClH/c1-3-4-5-6-7-11(10(2)20)19-9-18-12-13(15)16-8-17-14(12)19;/h8-11,20H,3-7H2,1-2H3,(H2,15,16,17);1H/t10-,11+;/m0./s1
• Clé InChI: VVDXNJRUNJMYOZ-VZXYPILPSA-N
• Informations sur le gène: human ... ADORA1(134), ADORA2A(135), ADORA2B(136), ADORA3(140)

Description

Description générale

EHNA is an adenosine deaminase inhibitor. It possesses antitumor action.

Application

EHNA hydrochloride has been used to treat microexplant culture to examine the direction and the motor responsible for the movement of autophagosomes in axons. It has also been used in nucleoside supplementation to inhibit the breakdown of deoxyadenosine by the enzyme adenosine deaminase.

Actions biochimiques/physiologiques

Adenosine deaminase inhibitor.

Caractéristiques et avantages

This compound is a featured product for Cyclic Nucleotide research. Click here to discover more featured Cyclic Nucleotide products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

This compound is featured on the Phosphodiesterases page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable
• Équipement de protection individuelle: Eyeshields, Gloves, type N95 (US)