E1378

Escin

≥95%, powder

• Synonyme(s) : Aescin
• CAS Number: 6805-41-0
• Numéro CE : 229-880-6
• Numéro MDL: MFCD00076054
• Code UNSPSC : 12352201
• ID de substance PubChem : 24894403
• Nomenclature NACRES : NA.25

Propriétés

• Source biologique: plant (Aesculus chinensis)
• Niveau de qualité: 200
• Essai: ≥95%
• Forme: powder
• Impuretés: ≤6.0% Water (Karl Fischer)
• Couleur: white
• Solubilité: methanol: 50 mg/mL, clear to slightly hazy, colorless to faintly yellow
• Chaîne SMILES: C\C=C(/C)C(=O)OC1[C@H](OC(C)=O)C2(CO)[C@H](O)C[C@]3(C)C(=CCC4C5(C)CCC(O[C@@H]6O[C@@H]([C@@H](O[C@@H]7O[C@H](CO)[C@@H](O)[C@H](O)[C@H]7O)[C@H](O)[C@H]6O[C@H]8O[C@H](CO)[C@@H](O)[C@H](O)[C@H]8O)C(O)=O)[C@](C)(CO)C5CCC34C)C2CC1(C)C
• InChI: 1S/C55H86O24/c1-10-23(2)46(71)79-43-44(72-24(3)60)55(22-59)26(17-50(43,4)5)25-11-12-30-51(6)15-14-32(52(7,21-58)29(51)13-16-53(30,8)54(25,9)18-31(55)61)75-49-41(77-48-38(67)36(65)34(63)28(20-57)74-48)39(68)40(42(78-49)45(69)70)76-47-37(66)35(64)33(62)27(19-56)73-47/h10-11,26-44,47-49,56-59,61-68H,12-22H2,1-9H3,(H,69,70)/b23-10+/t26?,27-,28-,29?,30?,31-,32?,33-,34-,35+,36+,37-,38-,39+,40+,41-,42+,43?,44+,47+,48-,49-,51?,52-,53?,54-,55?/m1/s1
• Clé InChI: AXNVHPCVMSNXNP-YSYFQUGBSA-N

Description

Application

Escin, a natural mixture of triterpenoid saponins isolated from horse chestnut (Aesculus hippocastanum) seeds, is used and studied as a vasoprotective anti-inflammatory, anti-edematous and anti-nociceptive agent. It may be used to study its pharmacokinetics, safety and efficacy as a chemosensitizer and modulator of NF-κ B cell signaling.

Autres remarques

To gain a comprehensive understanding of our extensive range of Polysaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Informations sur la sécurité

• Pictogrammes: GHS07
• Mention d'avertissement: Warning
• Mentions de danger: H302 + H332
• Conseils de prudence: P261 - P264 - P271 - P301 + P312 - P304 + P340 + P312 - P501
• Classification des risques: Acute Tox. 4 Inhalation - Acute Tox. 4 Oral
• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 2
• Équipement de protection individuelle: dust mask type N95 (US), Eyeshields, Gloves