E7280

Elafin

recombinant, expressed in Saccharomyces cerevisiae, powder, >90% (by MS, HPLC and SDS-PAGE),

• Synonyme(s) : Elastase-specific inhibitor, skin-derived antileukoprotease
• Numéro MDL: MFCD00146824
• Code UNSPSC : 12352202
• Nomenclature NACRES : NA.77

Propriétés

• Product Name: Elafin human, >90% (by MS, HPLC and SDS-PAGE), recombinant, expressed in Saccharomyces cerevisiae
• Produit recombinant: expressed in Saccharomyces cerevisiae
• Niveau de qualité: 200
• Essai: >90% (by MS, HPLC and SDS-PAGE)
• Forme: powder
• Puissance: 1.7 x 10-10 M K_i (human leukocyte elastase); 4.2 x 10-10 M K_i (human proteinase 3)
• Poids mol.: ~6 kDa
• Numéro d'accès UniProt: P19957
• Spectre d'activité de l'antibiotique: Gram-negative bacteria; Gram-positive bacteria
• Mode d’action: enzyme | inhibits
• Conditions d'expédition: ambient
• Température de stockage: −20°C
• Informations sur le gène: human ... PI3(5266)

Description

Description générale

Chemical structure: peptide

Actions biochimiques/physiologiques

Exhibits co-existent antimicrobial and antiproteolytic activities.1 Inhibits WAP-type four-disulfide core (WFDC) domain containing elastases. Antimicrobial spectrum: Gram-positive and Gram-negative bacteria.

Inhibitor of human leukocyte elastase and proteinase 3, originally isolated from the skin of patients with psoriasis. May protect against certain autoimmune tissue damage.

Inhibitor of human leukocyte elastase and proteinase 3, originally isolated from the skin of patients with psoriasis. May protect against certain autoimmune tissue damage. An elastase inhibitor which is an active fragment of elafin, as well as elafin itself, can also be found in bronchial carcinoma secretions.

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable
• Équipement de protection individuelle: Eyeshields, Gloves, type N95 (US)