F124

Furafylline

≥98% (HPLC), powder, caffeine inhibitor

• Synonyme(s) : 3-(2-Furanylmethyl)-3,7-dihydro-1,8-dimethyl-1H-purine-2,6-dione
• Formule empirique (notation de Hill) : C₁₂H₁₂N₄O₃
• CAS Number: 80288-49-9
• Poids moléculaire : 260.25
• Numéro MDL: MFCD00153799
• Code UNSPSC : 41106305
• ID de substance PubChem : 24278813
• Nomenclature NACRES : NA.77

Propriétés

• Product Name: Furafylline, ≥98% (HPLC)
• Niveau de qualité: 100
• Essai: ≥98% (HPLC)
• Forme: powder
• Couleur: white to beige
• Pf: 274-275 °C
• Solubilité: DMSO: 10 mg/mL, clear
• Température de stockage: room temp
• Chaîne SMILES: CN1C(=O)N(Cc2ccco2)c3nc(C)[nH]c3C1=O
• InChI: 1S/C12H12N4O3/c1-7-13-9-10(14-7)16(6-8-4-3-5-19-8)12(18)15(2)11(9)17/h3-5H,6H2,1-2H3,(H,13,14)
• Clé InChI: KGQZGCIVHYLPBH-UHFFFAOYSA-N
• Informations sur le gène: human ... CYP1A2(1544)

Description

Actions biochimiques/physiologiques

Furafylline (1,8-dimethyl-3-(2′ -furfuryl)methylxanthine) is a xanthine derivative. It is preferred in treating asthma. It serves as a N3-demethylation inhibitor of caffeine. Furafylline does not show much effect on human monooxygenase activities. It is considered as an efficient bronchodilator and as an inhibitor of anaphylactic reactions, when compared to theophylline.

Furafylline is a methyl xanthine derivative with longer duration of action than theophylline and an inhibitor of cytochrome P4501A2.

Caractéristiques et avantages

This compound is a featured product for ADME Tox and Cyclic Nucleotide research. Discover more featured ADME Tox and Cyclic Nucleotide products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable
• Équipement de protection individuelle: Eyeshields, Gloves, type N95 (US)