G002

Isoguvacine hydrochloride

solid

• Synonyme(s) : 1,2,3,6-Tetrahydro-4-pyridinecarboxylic acid hydrochloride
• Formule empirique (notation de Hill) : C₆H₉NO₂ · HCl
• CAS Number: 68547-97-7
• Poids moléculaire : 163.60
• Numéro MDL: MFCD00055192
• Code UNSPSC : 12352200
• ID de substance PubChem : 24278160
• Nomenclature NACRES : NA.77

Propriétés

• Forme: solid
• Niveau de qualité: 200
• Couleur: white
• Solubilité: H₂O: soluble (refrigerate if not used immediately.); methanol: slightly soluble; neutral and acidic solutions: stable (in basic solutions the free amine can oxidize easily)
• Chaîne SMILES: Cl[H].OC(=O)C1=CCNCC1
• InChI: 1S/C6H9NO2.ClH/c8-6(9)5-1-3-7-4-2-5;/h1,7H,2-4H2,(H,8,9);1H
• Clé InChI: SUWREQRNTXCCBL-UHFFFAOYSA-N
• Informations sur le gène: human ... GABRA1(2554), GABRA2(2555), GABRA3(2556), GABRA4(2557), GABRA5(2558), GABRA6(2559), GABRB1(2560), GABRB2(2561), GABRB3(2562)

Description

Application

Isoguvacine hydrochloride has been used as a γ-aminobutyric acid type A (GABA_A) receptor agonist:

• to study its effects on neuronal activity in rats
• to study its antiallodynic effect in rats
• to study its effects on baroreflex gains in rats

Actions biochimiques/physiologiques

Isoguvacine is a strong γ-aminobutyric acid A (GABA_A) receptor agonist.

Caractéristiques et avantages

This compound is a featured product for Neuroscience research. Click here to discover more featured Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

This compound is featured on the GABAA Receptors and GABAC Receptors pages of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Informations sur la sécurité

• Pictogrammes: GHS07
• Mention d'avertissement: Warning
• Mentions de danger: H315,H319,H335
• Conseils de prudence: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Classification des risques: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Organes cibles: Respiratory system
• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Équipement de protection individuelle: dust mask type N95 (US), Eyeshields, Gloves