G1513

Glycerol formal

47-67% 5-hydroxy-1,3-dioxane basis (GC), 33-53% 4-hydroxymethyl-1,3-dioxolane basis (GC)

• Formule empirique (notation de Hill) : C₄H₈O₃
• CAS Number: 99569-11-6
• Poids moléculaire : 104.10
• Beilstein: 103206
• Numéro MDL: MFCD10039829
• Code UNSPSC : 50161901
• ID de substance PubChem : 24895065
• Nomenclature NACRES : NA.25

Propriétés

• Niveau de qualité: 200
• Contient: ~0.02% 2,6-di-tert-butyl-4-methylphenol as stabilizer
• Composition: 5-hydroxy-1,3-dioxane, 47-67% GC ; 4-hydroxymethyl-1,3-dioxolane, 33-53% GC
• Indice de réfraction: n20/D 1.451 (lit.)
• pb: 192-193 °C (lit.)
• Densité: 1.203 g/mL at 25 °C (lit.)
• Chaîne SMILES: OCC1COCO1.OC2COCOC2
• InChI: 1S/2C4H8O3/c5-4-1-6-3-7-2-4;5-1-4-2-6-3-7-4/h2*4-5H,1-3H2
• Clé InChI: JIUMSISXCKWZTA-UHFFFAOYSA-N

Description

Description générale

Glycerol formal (GlyF) includes isomers, namely, 4-hydroxymethyl-1,3-dioxolane and 5-hydroxy-1,3-dioxane. It is a glycerol synthon with a combination of two 5- and 6-membered ring isomers.

Application

Glycerol formal is used to to solubilize water-insoluble compounds for subsequent aqueous dilution. It has been used as a chemical and dye emulsifier and as a cosolvent for drug delivery. Glycerol formal was used as a vehicle for antibiotic delivery in rats.

Informations sur la sécurité

• Classe de danger pour l'eau (WGK): WGK 3
• Équipement de protection individuelle: Eyeshields, Gloves, type ABEK (EN14387) respirator filter