H4131

Hemoglobin porcine

lyophilized powder

• Synonyme(s) : Hb
• CAS Number: 9008-02-0
• Numéro MDL: MFCD00131282
• Code UNSPSC : 12352202
• eCl@ss : 42030116
• Nomenclature NACRES : NA.61

Propriétés

• Source biologique: Porcine
• Forme: lyophilized powder
• Solubilité: H₂O: soluble 10 mg/mL
• Numéro d'accès UniProt: P02067; P02101
• Température de stockage: 2-8°C
• Informations sur le gène: pig ... HBB(407066), HBE1(407067)

Description

Description générale

Hemoglobin is the major component of red blood cells, and is responsible for their red color. Its normal concentration in erythrocytes is 34%. Hemoglobin is the most important respiratory protein of vertebrates by virtue of its ability to transport oxygen from the lungs to body tissues, and to facilitate the return transport of carbon dioxide.

Application

Hemoglobin from porcine was used to test the role of the L-arginine/nitric oxide pathway in relaxation of isolated human penile cavernous tissue and circumflex veins. It was also used to study the role of nitric oxide in neurogenic vasodilation of porcine cerebral artery.

Actions biochimiques/physiologiques

Oxygen transporter, NO scavenger

The Fe²⁺/Fe³⁺ balance is a physiological indicator of blood oxygenation. Deoxygenated hemoglobin accessorizes a feedback loop by reducing nitrite to NO, a vasodilator which enhances blood flow to oxygen-deprived tissues.

Attention

Since native hemoglobin is readily oxidized in air, these preparations may be predominantly methemoglobin.

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable
• Équipement de protection individuelle: Eyeshields, Gloves, type N95 (US)