I5657

Anti-Interleukin-22 Receptor, N-Terminal antibody produced in rabbit

~1 mg/mL, affinity isolated antibody, buffered aqueous solution

• Synonyme(s) : Anti-IL-22R
• Numéro MDL: MFCD04040433
• Code UNSPSC : 51111800
• Nomenclature NACRES : NA.41

Propriétés

• Source biologique: rabbit
• Niveau de qualité: 200
• Conjugué: unconjugated
• Forme d'anticorps: affinity isolated antibody
• Type de produit anticorps: primary antibodies
• Clone: polyclonal
• Forme: buffered aqueous solution
• Poids mol.: antigen ~62 kDa
• Espèces réactives: human
• Concentration: ~1 mg/mL
• Technique(s): ELISA: suitable; immunocytochemistry: suitable; immunofluorescence: suitable; immunohistochemistry: suitable; western blot: suitable
• Numéro d'accès UniProt: Q8N6P7
• Conditions d'expédition: dry ice
• Température de stockage: −20°C
• Modification post-traductionnelle de la cible: unmodified
• Informations sur le gène: human ... IL22RA1(58985)

Description

Immunogène

synthetic peptide corresponding to amino acids 31-46 of human IL-22 recptor precursor.

Actions biochimiques/physiologiques

Interleukin-22 (IL-22) belongs to the IL-10 family of T-cell associated cytokines, highly expressed by Th17 cell subset and also by cells of innate immunity system. The cellular effects of IL-22 are mediated by a heterodimeric receptor made up of IL-22 and IL-10Rβ. IL-22 signaling mediates proliferation of epithelial cells during inflammation mainly by the activation of STAT1 and STAT3 signaling.

Caractéristiques et avantages

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Forme physique

Solution in phosphate buffered saline containing 0.02% sodium azide.

Informations sur la sécurité

• Code de la classe de stockage: 10 - Combustible liquids