I9783

Monoclonal Anti-Importin α3 antibody produced in rat

clone 3D10, purified immunoglobulin, buffered aqueous solution

• Synonyme(s) : Anti-Imp α
• Numéro MDL: MFCD06798707
• Code UNSPSC : 12352203
• Nomenclature NACRES : NA.41

Propriétés

• Source biologique: rat
• Niveau de qualité: 200
• Conjugué: unconjugated
• Forme d'anticorps: purified immunoglobulin
• Type de produit anticorps: primary antibodies
• Clone: 3D10, monoclonal
• Forme: buffered aqueous solution
• Poids mol.: antigen ~60 kDa
• Espèces réactives: mouse, hamster, bovine, canine, rat, human, monkey
• Technique(s): microarray: suitable; western blot: 2-4 μg/mL using HeLa cell extract
• Isotype: IgG2a
• Numéro d'accès UniProt: O00629
• Conditions d'expédition: dry ice
• Température de stockage: −20°C
• Modification post-traductionnelle de la cible: unmodified
• Informations sur le gène: human ... KPNA4(3840) ; mouse ... Kpna4(16649) ; rat ... Kpna4(361959)

Description

Immunogène

recombinant mouse importin α3/Qip1.

Actions biochimiques/physiologiques

The gene KPNA4 (karyopherin subunit α 4) encodes a 16kDa protein, also referred to as importin α 3 belonging to the family of karyopherins (designated KPNA1 to KPNA4), that participates in the recognition of NLS (nuclear localization signal) sites and dock NLS-containing proteins destined for transport into the nuclear pore complex. It binds to translocon and participates in the sorting of INM (inner nuclear membrane)-directed integral membrane proteins. It associates with nucleoporins and functions in cargo-translocation across the nuclear membrane.

Forme physique

Solution in 0.01 M phosphate buffered saline, pH 7.4, and 15 mM sodium azide.

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informations sur la sécurité

• Code de la classe de stockage: 10 - Combustible liquids
• Classe de danger pour l'eau (WGK): nwg
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable