M6190

Monoclonal Anti-MYOD1 antibody produced in mouse

clone 5.2F, purified immunoglobulin, buffered aqueous solution

• Synonyme(s) : Anti-Myogenic Differentiation Antigen 1
• Numéro MDL: MFCD01323984
• Code UNSPSC : 12352203
• Nomenclature NACRES : NA.41

Propriétés

• Source biologique: mouse
• Niveau de qualité: 200
• Conjugué: unconjugated
• Forme d'anticorps: purified immunoglobulin
• Type de produit anticorps: primary antibodies
• Clone: 5.2F, monoclonal
• Forme: buffered aqueous solution
• Poids mol.: antigen 34 kDa
• Espèces réactives: human, rat, chicken, mouse
• Concentration: 1.0 mg/mL
• Technique(s): immunocytochemistry: suitable; immunohistochemistry (formalin-fixed, paraffin-embedded sections): 2-4 μg/mL; immunohistochemistry (frozen sections): 2-4 μg/mL; immunoprecipitation (IP): 2 μg using 1 mg protein lysate; western blot: 1 μg/mL (reacts with the ~45 kDa protein)
• Isotype: IgG2a
• Numéro d'accès UniProt: P15172
• Conditions d'expédition: wet ice
• Température de stockage: −20°C
• Informations sur le gène: human ... MYOD1(4654) ; mouse ... Myod1(17927) ; rat ... Myod1(337868)

Description

Description générale

Myogenic differentiation antigen 1 (MYOD1) is a nuclear protein which is expressed in skeletal muscles. It is part of the basic helix-loop-helix (bHLH) family of transcription factors. The gene encoding it is localized on human chromosome 11.

Immunogène

recombinant mouse MyoD1 protein.

Application

Monoclonal Anti-MYOD1 antibody produced in mouse has been used in:

• immunofluorescence staining at a 1:50 dilution
• western blotting
• immunostaining at a 1:300 dilution

Actions biochimiques/physiologiques

Myogenic differentiation antigen 1 (MYOD1) maybe involved in recruitment of enzymes like acetyltransferases and methyltransferases to myogenic enhancers in the human genome. It takes part in the regeneration of muscles and mediates muscle cell differentiation by activating cell cycle arrest.

Forme physique

Solution in phosphate buffered saline containing 0.08% sodium azide.

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informations sur la sécurité

• Code de la classe de stockage: 10 - Combustible liquids
• Classe de danger pour l'eau (WGK): nwg
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable