M8386

α,β-Methyleneadenosine 5′-diphosphate sodium salt

CD73 inhibitor

• Synonyme(s) : AMP-CP
• Formule empirique (notation de Hill) : C₁₁H₁₇N₅O₉P₂
• CAS Number: 104835-70-3
• Poids moléculaire : 425.23
• Numéro MDL: MFCD00070019
• Code UNSPSC : 41106305
• ID de substance PubChem : 24897249
• Nomenclature NACRES : NA.51

Propriétés

• Source biologique: synthetic (organic)
• Niveau de qualité: 200
• Essai: ≥98% (HPLC)
• Forme: powder
• Solubilité: water: 50 mg/mL, clear to slightly hazy, colorless
• Température de stockage: −20°C
• Chaîne SMILES: [Na].Nc1ncnc2n(cnc12)C3OC(COP(O)(=O)CP(O)(O)=O)C(O)C3O
• InChI: 1S/C11H17N5O9P2.Na.H/c12-9-6-10(14-2-13-9)16(3-15-6)11-8(18)7(17)5(25-11)1-24-27(22,23)4-26(19,20)21;;/h2-3,5,7-8,11,17-18H,1,4H2,(H,22,23)(H2,12,13,14)(H2,19,20,21);;
• Clé InChI: HEBWZOPLDYDXPJ-UHFFFAOYSA-N

Description

Application

α,β-Methyleneadenosine 5′-diphosphate sodium salt has been used as an ectonucleotidase/CD73 inhibitor to characterize the mode of adenosine production and as an inhibitor for in vitro studies.

Actions biochimiques/physiologiques

α, β-Methyleneadenosine 5′-diphosphate (AMP-CP) is an ADP analog that as an ability to inhibit ectonucleotidase/ CD73 inhibitor and is used to study adenosinergic signaling regulation via CD73/ecto-5′-nucleotidase.

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable