N7660

4-Nitrophenol

chromogenic, liquid

• Synonyme(s) : p-nitrophénol solution
• Formule empirique (notation de Hill) : C₆H₅NO₃
• CAS Number: 100-02-7
• Poids moléculaire : 139.11
• Numéro MDL: MFCD00007331
• Code UNSPSC : 12352204
• eCl@ss : 39032018
• ID de substance PubChem : 57654462
• Nomenclature NACRES : NA.28

Propriétés

• Product Name: 4-Nitrophenol solution, 10 mM
• Forme: liquid
• Niveau de qualité: 200
• Concentration: 10 mM
• Température de stockage: 2-8°C
• Chaîne SMILES: Oc1ccc(cc1)[N+]([O-])=O
• InChI: 1S/C6H5NO3/c8-6-3-1-5(2-4-6)7(9)10/h1-4,8H
• Clé InChI: BTJIUGUIPKRLHP-UHFFFAOYSA-N
• Informations sur le gène: human ... UGT1A4(54657)

Description

Description générale

4-Nitrophenol is a phenolic compound present as a chemical intermediate and breakdown product during the production of organophosphorus insecticide derivatives of parathion. It is an intermediate during the synthesis of paracetamol. 4-Nitrophenol is a chromogenic catalytic by product of the synthetic substrate 4-nitrophenyl phosphate. It is majorly used as a reference standard in alkaline phosphatase assay. 4-Nitrophenol is nonbiodegradable and its derivatives are used for herbicide and fungicide production.

Application

4-Nitrophenol solution has been used:

• in the generation of standard curve for quantifying alkaline phosphatase activity of mesenchymal stem cells
• bone marrow stromal cells (BMSCs)
• for quantifying β-hexosaminidase activity in HeLa cells
• as a standard for calorimetric determination of alkaline phosphatase activity at 405 nm
• for assessing the β-hexosamindase activity

Notes préparatoires

Prepared as a 1.39 mg/ml solution suitable for use as a calibrator in alkaline phosphatase assays (such as Bessey-Lowry-Brock method) using p-nitrophenol phosphate as a substrate.

Informations sur la sécurité

• Code de la classe de stockage: 10 - Combustible liquids
• Classe de danger pour l'eau (WGK): nwg
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable
• Équipement de protection individuelle: Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)