P5069

Prostaglandin F_2α tris salt

synthetic, suitable for cell culture

• Synonyme(s) : (5Z,9α,11α,13E,15S)-9,11,15-Trihydroxyprosta-5,13-dienoic acid tris salt, PGF_2α−Tris
• Formule empirique (notation de Hill) : C₂₀H₃₄O₅ · C₄H₁₁NO₃
• CAS Number: 38562-01-5
• Poids moléculaire : 475.62
• Beilstein: 4087514
• Numéro CE : 254-002-3
• Numéro MDL: MFCD00077863
• Code UNSPSC : 12352209
• ID de substance PubChem : 24898587
• Nomenclature NACRES : NA.77

Propriétés

• Source biologique: synthetic
• Essai: ≥99%
• Forme: powder
• Technique(s): cell culture | mammalian: suitable
• Solubilité: ethanol: 50 mg/mL, clear, colorless
• Conditions d'expédition: ambient
• Température de stockage: −20°C
• Chaîne SMILES: NC(CO)(CO)CO.[H][C@]1(C\C=C/CCCC(O)=O)[C@@H](O)C[C@@H](O)[C@]1([H])\C=C\[C@@H](O)CCCCC
• InChI: 1S/C20H34O5.C4H11NO3/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25;5-4(1-6,2-7)3-8/h4,7,12-13,15-19,21-23H,2-3,5-6,8-11,14H2,1H3,(H,24,25);6-8H,1-3,5H2/b7-4-,13-12+;/t15-,16+,17+,18-,19+;/m0./s1
• Clé InChI: IYGXEHDCSOYNKY-RZHHZEQLSA-N
• Informations sur le gène: human ... PTGFR(5737)

Description

Actions biochimiques/physiologiques

Luteolytic prostaglandin that induces parturition. Potent vasoconstrictor of pulmonary, coronary, and cerebral arteriole beds.

Luteolytic prostaglandin that induces parturition. Potent vasoconstrictor of pulmonary, coronary, and cerebral arteriole beds. A positive feedback loop between endometrial PG F_2α and luteal oxytocin is responsible for completion of luteolysis.

Luteolytic prostaglandin that induces parturition. Potent vasoconstrictor of pulmonary, coronary, and cerebral arteriole beds. Also stimulates contraction of smooth muscle, such as in bronchi, with possible involvement in asthma. This effect is at least partially mediated through tachykinin release.

Prostaglandin F2α is induced by uterine-produced oxytocin and acts on the corpus luteum to cause luteolysis and inhibit progesterone production.

Informations sur la sécurité

• Pictogrammes: GHS08,GHS07
• Mention d'avertissement: Danger
• Mentions de danger: H302,H360FD
• Conseils de prudence: P202 - P264 - P280 - P301 + P312 - P308 + P313 - P405
• Classification des risques: Acute Tox. 4 Oral - Repr. 1B
• Code de la classe de stockage: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• Classe de danger pour l'eau (WGK): WGK 3
• Équipement de protection individuelle: Eyeshields, Gloves, type P3 (EN 143) respirator cartridges