P5976

Anti-Platelet-Derived Growth Factor-BB antibody produced in goat

affinity isolated antibody, lyophilized powder

• Synonyme(s) : Anti-PDGF-BB
• Numéro MDL: MFCD00165456
• Code UNSPSC : 51111800
• Nomenclature NACRES : NA.41

Propriétés

• Source biologique: goat
• Niveau de qualité: 100
• Conjugué: unconjugated
• Forme d'anticorps: affinity isolated antibody
• Type de produit anticorps: primary antibodies
• Clone: polyclonal
• Forme: lyophilized powder
• Espèces réactives: human
• Technique(s): neutralization: suitable; western blot: suitable
• Numéro d'accès UniProt: P01127
• Température de stockage: −20°C
• Modification post-traductionnelle de la cible: unmodified
• Informations sur le gène: human ... PDGFB(5155)

Description

Description générale

Platelet-Derived Growth Factor-BB (PDGF-BB) is a cystine-linked homodimer that belongs to PDGF growth factor family and is expressed mainly by vascular endothelium, megakaryocytes and Leydig cells. It has key roles in regulating neurogenesis, producing proinflammatory cytokines by orbital fibroblasts in Graves′ Ophthalmopathy, cell proliferation, development, angiogenesis and cell survival. Anti-Platelet-Derived Growth Factor-BB antibody can be used for neutralizing the biological activity of recombinant human PDGF-BB, recombinant human-AB, natural human PDGF, rat PDGF-BB, and porcine PDGF-BB. It can also neutralize recombinant human PDGF-AA at 50-100 fold high IgG concentration. Goat Anti-Platelet-Derived Growth Factor-BB antibody reacts specifically with human PDGF-BB. The product has also shown less than 10% cross-reactivity for recombinant human PDGF-AA.

Immunogène

Recombinant human PDGF-BB expressed in Escherichia coli.

Application

Anti-Platelet-Derived Growth Factor-BB antibody can be used in immunoblotting and ELISA.

Forme physique

Lyophilized from 0.2 μm filtered solution in phosphate buffered saline pH 7.4 with 5% trehalose.

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 1
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable
• Équipement de protection individuelle: Eyeshields, Gloves, type N95 (US)