P8396

Piperacillin sodium salt

penicillin analog

• Formule empirique (notation de Hill) : C₂₃H₂₆N₅NaO₇S
• CAS Number: 59703-84-3
• Poids moléculaire : 539.54
• Beilstein: 5373920
• Numéro CE : 261-868-6
• Numéro MDL: MFCD00917471
• Code UNSPSC : 51282423
• ID de substance PubChem : 329820325
• Nomenclature NACRES : NA.85

Propriétés

• Niveau de qualité: 200
• Forme: powder
• Solubilité: H₂O: soluble 50 mg/mL
• Spectre d'activité de l'antibiotique: Gram-negative bacteria; Gram-positive bacteria
• Mode d’action: cell wall synthesis | interferes
• Température de stockage: 2-8°C
• Chaîne SMILES: [Na+].CCN1CCN(C(=O)N[C@@H](C(=O)N[C@H]2[C@H]3SC(C)(C)[C@@H](N3C2=O)C([O-])=O)c4ccccc4)C(=O)C1=O
• InChI: 1S/C23H27N5O7S.Na/c1-4-26-10-11-27(19(32)18(26)31)22(35)25-13(12-8-6-5-7-9-12)16(29)24-14-17(30)28-15(21(33)34)23(2,3)36-20(14)28;/h5-9,13-15,20H,4,10-11H2,1-3H3,(H,24,29)(H,25,35)(H,33,34);/q;+1/p-1/t13-,14-,15+,20-;/m1./s1
• Clé InChI: WCMIIGXFCMNQDS-IDYPWDAWSA-M

Description

Description générale

Chemical structure: ß-lactam

Application

Piperacillin is a semisynthetic, broad-spectrum ureidopenicillin antibiotic. It is derived from ampicillin. It has been used in pharmacokinetic studies in order to optimize antimicrobial therapy in patients with sepsis. It is used to study piperacillin hypersensitivity reactions and to study multidrug-resistant organisms.

Actions biochimiques/physiologiques

Piperacillin inhibits the last stage of bacterial cell wall synthesis by binding to certain penicillin-binding proteins (PBPs), which results in cell lysis. Cell lysis is mediated by bacterial cell wall autolytic enzymes. Piperacillin may interfere with autolysin inhibitors.

Conditionnement

1g,5g,10g

Autres remarques

Keep container tightly closed in a dry and well-ventilated place.Keep in a dry place.

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 2
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable
• Équipement de protection individuelle: Eyeshields, Gloves, type N95 (US)