S9944

Sibutramine hydrochloride monohydrate

≥98% (HPLC), solid

• Synonyme(s) : 1-(4-Chlorophenyl)-N,N-dimethyl-alpha-(2-methylpropyl)cyclobutanemethanamine hydrochloride monohydrate, Meridia, Reductil
• Formule empirique (notation de Hill) : C₁₇H₂₆ClN · HCl
• CAS Number: 84485-00-7
• Poids moléculaire : 316.31
• Numéro MDL: MFCD04039806
• Code UNSPSC : 12352116
• ID de substance PubChem : 329824638
• Nomenclature NACRES : NA.77

Propriétés

• Niveau de qualité: 100
• Essai: ≥98% (HPLC)
• Forme: solid
• Contrôle du médicament: USDEA Schedule IV
• Conditions de stockage: desiccated
• Couleur: white
• Solubilité: DMSO: >30 mg/mL; H₂O: insoluble
• Auteur: Abbott
• Température de stockage: room temp
• Chaîne SMILES: O.Cl.CC(C)CC(N(C)C)C1(CCC1)c2ccc(Cl)cc2
• InChI: 1S/C17H26ClN.ClH.H2O/c1-13(2)12-16(19(3)4)17(10-5-11-17)14-6-8-15(18)9-7-14;;/h6-9,13,16H,5,10-12H2,1-4H3;1H;1H2
• Clé InChI: KFNNPQDSPLWLCX-UHFFFAOYSA-N
• Informations sur le gène: human ... SLC6A2(6530), SLC6A3(6531), SLC6A4(6532)

Description

Application

Sibutramine hydrochloride monohydrate was used as standard to screen dietary supplements for sibutramine using ion mobility spectrometer.¹

Actions biochimiques/physiologiques

Sibutramine is a serotonin and noradrenaline reuptake inhibitor (SNRI).

Sibutramine is a serotonin and noradrenaline reuptake inhibitor (SNRI). It is an antiobesity drug, which decreases calorie intake and increases energy expanditure. Sibutramine antagonizes MPTP-induced dopamine depletion in mouse brain.

Caractéristiques et avantages

This compound was developed by Abbott. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable
• Équipement de protection individuelle: Eyeshields, Gloves, type N95 (US)