Accéder au contenu
MilliporeSigma
Toutes les photos(3)

Principaux documents

Voir toute la documentation

SBR00030

Sigma-Aldrich

Short Chain Fatty Acid Kit

0.2μM filtered

Synonyme(s) :

Sodium acetate, Sodium propionate, and Sodium butyrate

Se connecterpour consulter vos tarifs contractuels et ceux de votre entreprise/organisme
Toutes les photos(3)

About This Item

Code UNSPSC :
12352211
Nomenclature NACRES :
NA.25

Niveau de qualité

100

Conditionnement

pkg of 1 kit

Type de lipide

saturated FAs

Température de stockage

−20°C

Catégories apparentées

Description générale

Short chain fatty acids (SCFAs) are saturated fatty acids with less than 6 carbons. SCFAs are produced in the gut by microbial fermentation of dietary fibers.(1) The most important and researched SCFAs are Acetate (Ac), propionate (Pr) and butyrate (Bu).(2) SCFAs are predominantly found in the colon and cross the intestinal epithelium to the blood stream. SCFAs were found to be beneficial and effective in prevention of obesity, Non-alcoholic fatty liver disease and insulin resistance.(3,4)

Application

SCFAs can serve in various applications including in vitro and in vivo administration to study the effect on immune system activation(5), protect epithelial cells from LPS penetration by tight junction formation induction(6), effect insulin secretion(7) and more. In these studies, SCFAs were administrated in vitro at the following concentration range Acetate 1-10mM, propionate and butyrate 0.1-1mM and in vivo Acetate, 70 mM; propionate, 30 mM; butyrate, 20 mM.
Short-chain fatty acids (SCFAs) have diverse roles in various metabolic processes, and their measurement through metabolomics can provide valuable insights into several applications.

Actions biochimiques/physiologiques

Role
  • Regulate metabolism in the gut
  • Indicators of gut health and inflammation
  • Associated with gastrointestinal diseases such as IBS and other conditions such as obesity, colonic carcinogenesis, insulin sensitivity and ischemic stroke

Caractéristiques et avantages

  • High-quality chemical, suitable for mulitple research applications
  • Commonly employed in Metabolomics and Biochemical studies

Autres remarques

For additional information on our range of Biochemicals, please complete this form.

Code de la classe de stockage

10 - Combustible liquids

Faites votre choix parmi les versions les plus récentes :

Certificats d'analyse (COA)

Lot/Batch Number

It looks like we've run into a problem, but you can still download Certificates of Analysis from our Documents section.

Si vous avez besoin d'assistance, veuillez contacter Service Clients

Déjà en possession de ce produit ?

Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.

Consulter la Bibliothèque de documents

Notre équipe de scientifiques dispose d'une expérience dans tous les secteurs de la recherche, notamment en sciences de la vie, science des matériaux, synthèse chimique, chromatographie, analyse et dans de nombreux autres domaines..

Contacter notre Service technique