SBR00119

Sarecycline Hydrochloride

• Synonyme(s) : P-005672 HCl, P005672 HCl
• Formule empirique (notation de Hill) : C₂₄H₃₀ClN₃O₈
• CAS Number: 1035979-44-2
• Poids moléculaire : 523.96
• Code UNSPSC : 51101500

Propriétés

• Conditions de stockage: under inert gas
• Niveau de qualité: 100
• Spectre d'activité de l'antibiotique: Gram-negative bacteria; Gram-positive bacteria
• Mode d’action: protein synthesis | inhibits
• Conditions d'expédition: ambient
• Température de stockage: 2-8°C
• Chaîne SMILES: CN(C)[C@H]1[C@H]2C[C@H]3CC4=C(C=CC(=C4C(=C3C(=O)[C@@]2(C(=C(C1=O)C(=O)N)O)O)O)O)CN(C)OC.Cl
• InChI: 1S/C24H29N3O8.ClH/c1-26(2)18-13-8-11-7-12-10(9-27(3)35-4)5-6-14(28)16(12)19(29)15(11)21(31)24(13,34)22(32)17(20(18)30)23(25)33;/h5-6,11,13,18,28-29,32,34H,7-9H2,1-4H3,(H2,25,33);1H/t11-,13-,18-,24-;/m0./s1
• Clé InChI: JGPBDCKZLBSHOI-FIPJBXKNSA-N

Description

Description générale

Sarecycline Hydrochloride is an antibioitc which belongs to the class of couponds know as tetracycline antibiotics. It is a modified derivative of naturally occurring tetracyclines. Sarecycline Hydrochloride is active against a wide range of Gram-positive and Gram-negative bacteria,

Actions biochimiques/physiologiques

Sarecycline Hydrochloride iinhibits bacterial protein synthesis by binding to the 30S subunit of the bacterial ribosome. Specifically, it binds to the A site of the ribosome and blocks the attachment of aminoacyl-tRNA molecules to the ribosome, which is necessary for the addition of new amino acids to the growing polypeptide chain. This ultimately leads to the inhibition of bacterial protein synthesis and reduction in bacteria that are associated with acne.

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable