SCP0200

Neuromedin N

• Synonyme(s) : NMN-125, NN, NT/N, NmN
• Formule empirique (notation de Hill) : C₃₈H₆₃N₇O₈
• Poids moléculaire : 745.95
• Code UNSPSC : 12352200
• Nomenclature NACRES : NA.32

Propriétés

• Essai: ≥95% (HPLC)
• Forme: lyophilized
• Composition: Peptide Content, ≥65%
• Conditions de stockage: protect from light
• Numéro d'accès UniProt: P30990
• Température de stockage: −20°C
• Informations sur le gène: human ... NTS(4922)

Description

Amino Acid Sequence

Lys-Ile-Pro-Tyr-Ile-Leu

Actions biochimiques/physiologiques

Neuromedin N is a hexapeptide that is related to neurotensin. Its precursor, proneuromedin N, is expressed in the adrenals, brain, gut and also in several cancers. In myoelectric activity, it has been reported to act in a similar manner as neurotensin, at a lesser degree of potency. Neuromedin N has been shown to increase the chemotaxis capacity of mouse lymphocytes and to modulate function of the hypothalamo-pituitary-adrenocortical axis in rats. Neuromedin N has been proposed to exert its actions via increase in intracellular Ca²⁺ concentration, although this is uncertain.

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable