SML0043

Racecadotril

≥98% (HPLC)

• Synonyme(s) : (RS)-Benzyl N-[3-(acetylthio)-2-benzylpropanoyl]glycinate, (±)-Acetorphan, Acetorphan, Cadotril, Redotil, Tiorfan, Zedott
• Formule empirique (notation de Hill) : C₂₁H₂₃NO₄S
• CAS Number: 81110-73-8
• Poids moléculaire : 385.48
• Numéro MDL: MFCD00865520
• Code UNSPSC : 12352200
• ID de substance PubChem : 329825113
• Nomenclature NACRES : NA.77

Propriétés

• Niveau de qualité: 100
• Essai: ≥98% (HPLC)
• Forme: powder
• Couleur: white to tan
• Solubilité: DMSO: ≥44 mg/mL
• Température de stockage: room temp
• Chaîne SMILES: CC(=O)SCC(Cc1ccccc1)C(=O)NCC(=O)OCc2ccccc2
• InChI: 1S/C21H23NO4S/c1-16(23)27-15-19(12-17-8-4-2-5-9-17)21(25)22-13-20(24)26-14-18-10-6-3-7-11-18/h2-11,19H,12-15H2,1H3,(H,22,25)
• Clé InChI: ODUOJXZPIYUATO-UHFFFAOYSA-N

Description

Application

Racecadotril may be used to study enkephalinase-mediated cellular changes.

Actions biochimiques/physiologiques

Inhibition of enkephalinase by Racecadotril prevents the breakdown of enkephalins in the gastrointestinal tract. This reduces secretion of water and electrolytes into the gut without affecting the mobility.

Neutral endopeptidase inhibitor; antidiarrheal

Racecadotril is a neutral endopeptidase inhibitor, an antidiarrheal drug which acts as a peripherally acting enkephalinase inhibitor.

Caractéristiques et avantages

This compound is featured on the Neuropeptidases page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Informations sur la sécurité

• Pictogrammes: GHS07,GHS09
• Mention d'avertissement: Warning
• Mentions de danger: H302,H400
• Conseils de prudence: P273 - P301 + P312 + P330
• Classification des risques: Acute Tox. 4 Oral - Aquatic Acute 1
• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable