SML0060

NB001

≥98% (HPLC)

• Synonyme(s) : 5-[[2-(6-Amino-9H-purin-9-yl)ethyl]amino]-1-pentanol; HTS 09836
• Formule empirique (notation de Hill) : C₁₂H₂₀N₆O
• CAS Number: 686301-48-4
• Poids moléculaire : 264.33
• Numéro MDL: MFCD03086724
• Code UNSPSC : 41106305
• ID de substance PubChem : 329825126
• Nomenclature NACRES : NA.77

Propriétés

• Niveau de qualité: 100
• Essai: ≥98% (HPLC)
• Forme: powder
• Couleur: white to tan
• Solubilité: H₂O: ≥24 mg/mL
• Température de stockage: −20°C
• Chaîne SMILES: Nc1ncnc2n(CCNCCCCCO)cnc12
• InChI: 1S/C12H20N6O/c13-11-10-12(16-8-15-11)18(9-17-10)6-5-14-4-2-1-3-7-19/h8-9,14,19H,1-7H2,(H2,13,15,16)
• Clé InChI: CVPTTZZCRDVGSU-UHFFFAOYSA-N

Description

Application

NB001 may be used in adenylyl cyclase 1-mediated cell signaling studies.

Actions biochimiques/physiologiques

NB001, originally believed to be a selective inhibitor of adenylyl cyclase 1 (AC1), new evidence suggests NB001 does not interact with AC1 directly. NB001 may reduce cAMP accumulation in cells through an unknown mechanism that is dependent on AC1.

Caractéristiques et avantages

This compound is a featured product for Cyclic Nucleotide research. Click here to discover more featured Cyclic Nucleotide products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

This compound is featured on the Adenylyl cyclases page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Informations sur la sécurité

• Pictogrammes: GHS06
• Mention d'avertissement: Danger
• Mentions de danger: H301
• Conseils de prudence: P264 - P270 - P301 + P310 - P405 - P501
• Classification des risques: Acute Tox. 3 Oral
• Code de la classe de stockage: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable