SML0119

Acrivastine

≥98% (HPLC)

• Synonyme(s) : (E)-6-((E)-3-(1-Pyrrolidinyl)-1-p-tolylpropenyl)-2-pyridineacrylic acid
• Formule empirique (notation de Hill) : C₂₂H₂₄N₂O₂
• CAS Number: 87848-99-5
• Poids moléculaire : 348.44
• Numéro MDL: MFCD00869830
• Code UNSPSC : 12352200
• ID de substance PubChem : 329825170
• Nomenclature NACRES : NA.77

Propriétés

• Niveau de qualité: 100
• Essai: ≥98% (HPLC)
• Forme: powder
• Conditions de stockage: desiccated
• Couleur: white to beige
• Solubilité: DMSO: >2 mg/mL (warmed)
• Température de stockage: 2-8°C
• Chaîne SMILES: Cc1ccc(cc1)\C(=C/CN2CCCC2)c3cccc(\C=C\C(O)=O)n3
• InChI: 1S/C22H24N2O2/c1-17-7-9-18(10-8-17)20(13-16-24-14-2-3-15-24)21-6-4-5-19(23-21)11-12-22(25)26/h4-13H,2-3,14-16H2,1H3,(H,25,26)/b12-11+,20-13+
• Clé InChI: PWACSDKDOHSSQD-IUTFFREVSA-N
• Informations sur le gène: human ... HRH1(3269)

Description

Application

Acrivastine has been used as an antihistamine to investigate the relation between the increased residence time of antihistamine at the histamine H1 receptor (H1R) and the duration of effective target-inhibition by this antagonist.

Actions biochimiques/physiologiques

Acrivastine is a second-generation H1-receptor antagonist.

Acrivastine is a second-generation antihistamine, an H1-receptor antagonist.

Acrivastine is a second-generation antihistamine. It is a derivative of first-generation compound triprolidine. Acrivastine is effectively used for treating allergic diseases including cholinergic urticaria and histamine-medicated dermatoses.

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable