SML0216

Brinzolamide

≥98% (HPLC)

• Synonyme(s) : (5R)-5-Ethylamino-3-(3-methoxypropyl)-2,2-dioxo-2?6,9-dithia-3-azabicyclo[4.3.0]nona-7,10-diene-8-sulfonamide, (R)- 4-(ethylamino)-3,4-dihydro-2-(3-methoxypropyl)-2H-Thieno[3,2-e]-1,2-thiazine-6-sulfonamide 1,1-dioxide, AL 4862
• Formule empirique (notation de Hill) : C₁₂H₂₁N₃O₅S₃
• CAS Number: 138890-62-7
• Poids moléculaire : 383.51
• Numéro MDL: MFCD08067749
• Code UNSPSC : 12352200
• ID de substance PubChem : 329825236
• Nomenclature NACRES : NA.77

Propriétés

• Niveau de qualité: 100
• Essai: ≥98% (HPLC)
• Forme: powder
• Conditions de stockage: desiccated
• Couleur: white to beige
• Solubilité: DMSO: ≥10 mg/mL
• Température de stockage: −20°C
• Chaîne SMILES: CCN[C@H]1CN(CCCOC)S(=O)(=O)c2sc(cc12)S(N)(=O)=O
• InChI: 1S/C12H21N3O5S3/c1-3-14-10-8-15(5-4-6-20-2)23(18,19)12-9(10)7-11(21-12)22(13,16)17/h7,10,14H,3-6,8H2,1-2H3,(H2,13,16,17)/t10-/m0/s1
• Clé InChI: HCRKCZRJWPKOAR-JTQLQIEISA-N
• Informations sur le gène: human ... CA2(760)

Description

Description générale

Brinzolamide is a small molecular weight compound that has an ability to bind melanin. This drug is used in ocular therapy.

Application

Brinzolamide has been used as a melanin binding compound or drug in melanin binding assays. It has also been used as a carbonic anhydrase inhibitor (CAI).

Actions biochimiques/physiologiques

Brinzolamide is a carbonic anhydrase II inhibitor

Brinzolamide is a carbonic anhydrase II inhibitor used to lower intraocular pressure.

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable