SML0308

Carbazeran

≥95% (HPLC)

• Synonyme(s) : N-Ethyl-carbamic acid 1-(6,7-dimethoxy-1-phthalazinyl)-4-piperidinyl ester, UK 31557
• Formule empirique (notation de Hill) : C₁₈H₂₄N₄O₄
• CAS Number: 70724-25-3
• Poids moléculaire : 360.41
• Numéro MDL: MFCD00867107
• Code UNSPSC : 41106305
• ID de substance PubChem : 329825313
• Nomenclature NACRES : NA.77

Propriétés

• Niveau de qualité: 100
• Essai: ≥95% (HPLC)
• Forme: powder
• Conditions de stockage: desiccated
• Couleur: white to beige
• Solubilité: DMSO: ≥2 mg/mL at warmed
• Température de stockage: 2-8°C
• Chaîne SMILES: CCNC(=O)OC1CCN(CC1)c2nncc3cc(OC)c(OC)cc23
• InChI: 1S/C18H24N4O4/c1-4-19-18(23)26-13-5-7-22(8-6-13)17-14-10-16(25-3)15(24-2)9-12(14)11-20-21-17/h9-11,13H,4-8H2,1-3H3,(H,19,23)
• Clé InChI: QJGVXJYGDBSPSJ-UHFFFAOYSA-N

Description

Description générale

Carbazeran is usedin the treatment of heart failure.

Actions biochimiques/physiologiques

Aldehyde oxidase (AO) substrate; inotropic agent and phosphodiesterase inhibitor

Carbazeran is an Aldehyde oxidase (AO) substrate and a phosphodiesterase inhibitor that produces concentration-dependent positive inotropic responses. In humans, the compound is almost completely cleared via 4-hydroxylation to the phthalazinone metabolite by AO.

Caractéristiques et avantages

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Informations sur la sécurité

• Pictogrammes: GHS06
• Mention d'avertissement: Danger
• Mentions de danger: H301
• Conseils de prudence: P264 - P270 - P301 + P310 - P405 - P501
• Classification des risques: Acute Tox. 3 Oral
• Code de la classe de stockage: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable