SML0450

5-BDBD

≥98% (HPLC)

• Synonyme(s) : 5-(3-Bromophenyl)-1,3-dihydro-2H-Benzofuro[3,2-e]-1,4-diazepin-2-one
• Formule empirique (notation de Hill) : C₁₇H₁₁BrN₂O₂
• CAS Number: 768404-03-1
• Poids moléculaire : 355.19
• Numéro MDL: MFCD18086878
• Code UNSPSC : 12352200
• ID de substance PubChem : 329824730
• Nomenclature NACRES : NA.77

Propriétés

• Niveau de qualité: 100
• Essai: ≥98% (HPLC)
• Forme: powder
• Couleur: white to beige
• Solubilité: DMSO: 15 mg/mL (clear solution)
• Température de stockage: 2-8°C
• Chaîne SMILES: Brc1cccc(c1)C2=NCC(=O)Nc3c2oc4ccccc34
• InChI: 1S/C17H11BrN2O2/c18-11-5-3-4-10(8-11)15-17-16(20-14(21)9-19-15)12-6-1-2-7-13(12)22-17/h1-8H,9H2,(H,20,21)
• Clé InChI: NKYMVQPXXTZHSF-UHFFFAOYSA-N

Description

Actions biochimiques/physiologiques

5-BDBD is a specific inhibitor of P2X4.

5-BDBD is a specific inhibitor of P2X4. The compound inhibits P2X4 currents in CHO cells with an IC₅₀ of 500 nM.

In native tissues, 5-BDBD is considered as a beneficial antagonist to analyze the effect of P2X receptors (P2XRs) subtype P2X4R.

Caractéristiques et avantages

This compound is featured on the P2 Receptors: P2X Ion Channel Family page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable